Expected to be diagnosed in 2% of men and 1% of women in the U.S., kidney cancer has traditionally been one of the most challenging cancers to treat. Until 2005, only one drug had been approved by the Food and Drug Administration ...
Oct 14, 2022
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Scientists at St. Jude Children's Research Hospital have shown how a protein responsible for adapting to low oxygen conditions (hypoxia), causes increased expression of fetal hemoglobin (HbF) in adults. The finding has implications ...
Oct 12, 2022
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One of the many risks associated with heart attacks and cardiac surgery is acute kidney injury, a serious condition that in some cases can lead to kidney failure.
Oct 7, 2022
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Acute kidney injury (AKI) is a frequent complication associated with various diseases and particularly affects patients on intensive care units. However, the mechanisms underlying AKI are incompletely understood. Just recently, ...
Oct 5, 2022
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Macrophages are immune cells that engulf and digest pathogens, cancer cells or cellular debris. The kidneys—like other tissues in the body—contain kidney resident macrophages, or KRMs, from the time of birth. These KRMs ...
Sep 28, 2022
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DNA damage is one of the foundational causes of cancer. But researchers have now found that deliberately causing DNA damage—by delivering additional treatments like radiotherapy—could improve the effectiveness of immunotherapy ...
Sep 20, 2022
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Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern ...
Sep 16, 2022
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Researchers at Johns Hopkins Medicine report that an experimental drug first developed to treat kidney disease prolongs survival and improves muscle function in mice genetically engineered to develop a severe form of Duchenne ...
Sep 13, 2022
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The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) will present data from PROSPER RCC (EA8143), the first randomized phase 3 trial of neoadjuvant immunotherapy in patients with kidney cancer. Patients with high-risk renal ...
Sep 8, 2022
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Physiologists at the University of Nevada, Reno have identified two ion channels necessary for urine to flow from the kidneys to the ureters. A calcium-activated chloride channel and a voltage-dependent calcium channel are ...
Sep 1, 2022
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