Genetics

Epigenetic profiling identifies potential COPD treatment targets

Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease). Using high-resolution epigenetic profiling, German and British scientists ...

Genetics

Genetics and diet influence bile acid homeostasis

EPFL scientists have used a systems genetics approach to unravel novel genetic and environmental modulators of bile acid homeostasis. Their findings provide new insights into the regulatory mechanisms of bile acid homeostasis ...

Diabetes

Type 1 diabetes can be predicted with epigenetic changes

Children who develop type 1 diabetes show epigenetic changes in the cells of their immune system already before the antibodies of the disease are detected in their blood. The findings of two new studies offer new opportunities ...

Psychology & Psychiatry

Why some people find it harder to be happy

The self-help industry is booming, fuelled by research on positive psychology—the scientific study of what makes people flourish. At the same time, the rates of anxiety, depression and self-harm continue to soar worldwide. ...

Psychology & Psychiatry

Brain gene expression patterns altered by chronic opioid use

The epidemic of opioid abuse affects millions of people worldwide, but researchers know surprisingly little about the molecular changes caused by opioids in the human brain. A new study, which appears in Biological Psychiatry, ...

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