St. Jude Children's Research Hospital scientists have improved chimeric antigen receptor (CAR) T–cell immunotherapy for acute myeloid leukemia (AML), demonstrating better efficacy in the lab.
Feb 12, 2024
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In many cancers, such as ovarian cancer, each round of chemotherapy kills the majority of cancer cells, while a small population of them survives through treatment. These cells are typically more resistant for the next cycle ...
Feb 12, 2024
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UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications beyond HIV biology.
Jan 24, 2024
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Researchers at Karolinska Institutet and SciLifeLab demonstrate in a new study published in iScience how they can identify substances that can deactivate an enzyme responsible for chemotherapy resistance in cancer cells. ...
Jan 18, 2024
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A recent study has reported that changes in mice sperm microRNAs brought about by aging may affect the growth and development of offspring. The finding adds to the growing literature on the effects of paternal aging on offspring.
Jan 12, 2024
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Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn's disease. This protein, known as ...
Jan 11, 2024
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Pancreatic cancer presents a challenging prognosis, marked by a five-year overall survival rate of merely 12.5%. Diagnosis frequently occurs at an advanced stage, characterized by metastasis to distant sites. The intricate ...
Jan 11, 2024
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Mice reach the twilight of their lives at around age two, the rough equivalent of 80 in human years. And when researchers introduce specific mutations into mice and then age them up, the mice can grow forgetful and irritable—eventually ...
Jan 10, 2024
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In-vitro-fertilization (IVF), a fertility treatment that involves fertilizing eggs in the laboratory and later implanting them in the uterus, has been a source of hope for many people struggling to conceive. However, the ...
Jan 10, 2024
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Researchers at Weill Cornell Medicine have cataloged the cellular response to stroke in a preclinical model, identifying the immune cells involved and the roles they may play in the days and weeks following a stroke.
Jan 10, 2024
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