News tagged with mutant cells
Modified protein could become first effective treatment for vitiligo
Loyola University Chicago Stritch School of Medicine researchers have developed a genetically modified protein that dramatically reverses the skin disorder vitiligo in mice, and has similar effects on immune ...
Medical research
Feb 27, 2013 |
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Research uncovers a potential link between Parkinson's and visual problems
The most common genetic cause of Parkinson's is not only responsible for the condition's distinctive movement problems but may also affect vision, according to new research by scientists at the University of York.
Parkinson's & Movement disorders
Feb 15, 2013 |
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Researchers generate mutant mouse model useful in treatment of neuromuscular diseases
Researchers at the University of Granada have produced for the first time in the world mice lacking the coenzyme Q10, a rare mitochondrial disease prevailingly affecting children. The researchers needed three ...
Genetics
Jan 29, 2013 |
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Diabetes drug could hold promise for lung cancer patients
Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases ...
Cancer
Jan 29, 2013 |
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Mouse mutant opens new path for birth defect research
(Medical Xpress)—According to the Centers for Disease Control, nearly 3 of every 100 babies in the U.S. are born with a birth defect. Among boys, one of the most common defects is the displacement of the ...
Medical research
Jan 16, 2013 |
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Possible role for Huntington's gene discovered
About 20 years ago, scientists discovered the gene that causes Huntington's disease, a fatal neurodegenerative disorder that affects about 30,000 Americans. The mutant form of the gene has many extra DNA ...
Genetics
Jan 16, 2013 |
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New technique catalogs lymphoma-linked genetic variations
(Medical Xpress)—As anyone familiar with the X-Men knows, mutants can be either very good or very bad—or somewhere in between. The same appears true within cancer cells, which may harbor hundreds of mutations that set ...
Cancer
Dec 27, 2012 |
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A key gene for brain development
(Medical Xpress)—Neurobiologists at the Research institute of Molecular Pathology (IMP) in Vienna have discovered one of the key genes required to make a brain. Mutations in this gene, called TUBB5, cause ...
Genetics
Dec 14, 2012 |
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Targeting downstream proteins in cancer-causing pathway shows promise in cell, animal model
The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell's powerhouse, making it dependent on the amino acid glutamine for survival. In fact, 40 percent of all "hard-to-treat" cancers have a ...
Cancer
Nov 13, 2012 |
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First trial in humans of 'minicells': A completely new way of delivering anti-cancer drugs
A completely new way of delivering anti-cancer drugs to tumours, using 'minicells' derived from bacteria, has been tested for the first time in humans and found to be safe, well-tolerated and even induced stable disease in ...
Cancer
Nov 08, 2012 |
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Study shows underlying connection between 'good' cholesterol and collagen in heart health
(Medical Xpress)—Arterial stiffening has long been considered a major risk factor for cardiovascular disease. Keeping arteries soft and supple might reduce disease risk, but the mechanisms of how arteries ...
Cardiology
Nov 01, 2012 |
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Stay-at-home transcription factor prevents neurodegeneration
A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow ...
Medical research
Oct 29, 2012 |
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Transcription factor Prox1 controls hippocampal cellular diversity, researchers find
As is true of many brain structures, the hippocampus, which plays a central role in memory and learning, is made up of multiple cell types organized into domains controlling different functions. Distinct ...
Neuroscience
Oct 16, 2012 |
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New mouse model of debilitating lung disease suggests potential treatment regimen
LAM, short for pulmonary lymphangioleiomyomatosis, affects about 1 in 10,000 women of childbearing age and is characterized by proliferation of smooth muscle-like cells in the lung, destruction of lung tissue, and growth ...
Medical research
Oct 03, 2012 |
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Treating ovarian cancer: New pathways through genetics
A new discovery that sheds light on the genetic make up of ovarian cancer cells could explain why some women survive longer than others with this deadly disease. A multi-disciplinary team led by the Research Institute of ...
Cancer
Sep 24, 2012 |
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