Declining levels of the protein BubR1 occur when both people and animals age, and contribute to cell senescence or deterioration, weight loss, muscle wasting and cataracts. Mayo Clinic researchers have shown that adult progenitor ...
Apr 18, 2013
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As is true of many brain structures, the hippocampus, which plays a central role in memory and learning, is made up of multiple cell types organized into domains controlling different functions. Distinct from many other brain ...
Oct 16, 2012
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A team of researchers led by Dr. Sandra Castillo and Dr. Mariona Graupera, from the Josep Carreras Leukaemia Research Institute and CIBERONC, have found the AKT inhibitor miransertib could be a new, effective molecular treatment ...
Jun 14, 2022
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A new view of a protein frequently mutated in pituitary tumors is overturning conventional wisdom and could point to novel targets for cancer drugs.
Apr 13, 2018
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Mutations in HIV that develop during the first few weeks of infection may play a critical role in undermining a successful early immune response, a finding that reveals the importance of vaccines targeting regions of the ...
Mar 8, 2012
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Scientists now have clues to how a gene mutation discovered in families affected with congenital heart disease leads to underdevelopment of the walls that separate the heart into four chambers. A Nationwide Children's Hospital ...
Jun 26, 2012
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Researchers at A*STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers. This strategy works by sabotaging the ability of ...
Sep 18, 2013
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A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.
May 1, 2013
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Stanford Medicine researchers have found that a common blood condition associated with several diseases may have a protective effect against Alzheimer's disease.
Jun 28, 2023
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Acute myeloid leukemia, a common leukemia in adults, is characterized by aberrant proliferation of cancerous bone marrow cells. Activating mutations in a protein receptor known as FLT3 receptor are among the most prevalent ...
Jul 16, 2012
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