News tagged with mutation rates
Surgery can dramatically reduce genetic cancer risk
Women whose genes put them at a high risk of contracting breast cancer can dramatically reduce the danger by having a double mastectomy—but not eliminate it altogether, experts say.
Cancer
May 14, 2013 |
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Naturally occurring substance proves effective against deadly skin cancer in laboratory tests
For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin ...
Cancer
Apr 10, 2013 |
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Association between genetic mutation and risk of death for patients with thyroid cancer
Presence of the genetic mutation BRAF V600E was significantly associated with increased cancer-related death among patients with papillary thyroid cancer (PTC); however, because overall mortality in PTC is low and the association ...
Cancer
Apr 09, 2013 |
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First genetic factor in prostate cancer prognosis identified
Patients with prostate cancer and hereditary mutations in the BRCA2 gene have a worse prognosis and lower survival rates than do the rest of the patients with the disease. This is the main conclusion to come out of a study ...
Cancer
Apr 09, 2013 |
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Patients with BRCA1 mutations, but not BRCA2 mutations, had poorer prognosis compared with noncarriers
Patients with breast cancer who had a BRCA1 mutation had significantly worse overall and recurrence-free survival rates compared with patients without BRCA mutations, but no evidence for a difference in survival was found ...
Cancer
Apr 09, 2013 |
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BRAF mutation less common among patients with melanoma in Ireland
The BRAF mutation believed to drive disease in about half of patients with melanoma was found to occur at a significantly lower frequency in patients with melanoma in Ireland, according to data presented at the AACR Annual ...
Cancer
Apr 08, 2013 |
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HIV antibodies that are worth the wait
An effective vaccine against HIV-1 remains elusive, but one promising strategy focuses on designer antibodies that have much broader potency than most normal, exquisitely specific antibodies. These broadly ...
HIV & AIDS
Mar 28, 2013 |
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Two-pronged immune cell approach could lead to universal shot against flu
Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific ...
Medical research
Mar 14, 2013 |
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'Defective' virus surprisingly plays major role in spread of disease
(Medical Xpress)—Defective viruses, thought for decades to be essentially garbage unrelated to the transmission of normal viruses, now appear able to play an important role in the spread of disease, new ...
Diseases, Conditions, Syndromes
Feb 28, 2013 |
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Drug shown to reverse radioiodine resistance in some advanced thyroid cancers
The experimental drug selumetinib may allow some patients with advanced thyroid cancer to overcome resistance to radioiodine (RAI), the most effective therapy for the disease, according to new research from Memorial Sloan-Kettering ...
Cancer
Feb 14, 2013 |
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Strong genetic selection against some psych disorders
(HealthDay)—Different evolutionary mechanisms likely support the persistence of various psychiatric disorders, according to a study published in the January issue of JAMA Psychiatry.
Psychology & Psychiatry
Jan 05, 2013 |
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Microevolutionary analysis of Clostridium difficile genomes to investigate transmission
Over recent years, hospital-acquired Clostridium difficile infections have been a significant problem in UK hospitals and globally. There have been concerns that infections may be due to transmission between symptomatic patien ...
Diseases, Conditions, Syndromes
Dec 20, 2012 |
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Genomic 'hotspots' offer clues to causes of autism, other disorders
An international team, led by researchers from the University of California, San Diego School of Medicine, has discovered that "random" mutations in the genome are not quite so random after all. Their study, ...
Genetics
Dec 20, 2012 |
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New assessment reveals value of second embryo biopsy for women of advanced maternal age
An elegant new study confirms that the most commonly used method of screening for embryo abnormalities following in vitro fertilization (IVF) does accurately predict the success of embryo transplantation for younger women, ...
Obstetrics & gynaecology
Nov 07, 2012 |
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Big, rapid gains made in human lifespan: study
(HealthDay)—It's said that life is short. But people living in developed countries typically survive more than twice as long as their hunter-gatherer ancestors did, making 72 the new 30, according to new ...
Medical research
Oct 15, 2012 |
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