Scientists at the Francis Crick Institute have found that deleting two genes that encode key enzyme proteins (kinases NDR1 and NDR2), impairs the health of neurons and leads to neurodegeneration in young mice as well as in ...
Nov 30, 2022
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A new study from UCLA researchers provides a strategy for finding treatments optimally tailored for women and men to prevent cognitive decline in aging as well as progression of neurodegenerative diseases by leveraging sex ...
Nov 4, 2022
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Dementia encompasses a range of neurodegenerative conditions that lead to memory loss and cognitive deficiencies and affect some 55 million people worldwide. Yet despite its prevalence, there are few effective treatments, ...
Oct 27, 2022
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Alzheimer's disease (AD) currently has no cure and is predicted to affect over 100 million people worldwide by 2050. Ongoing research is focused on two key neurotoxic proteins: amyloid beta (Aβ) and tau. While these proteins ...
Oct 17, 2022
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While the role of the blood-brain barrier has long been appreciated for its ability to maintain precise control over what molecules can enter the nervous system, very little is known about how the cells that form the barrier ...
Aug 15, 2022
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People who eat a healthy diet during middle age have a larger brain volume than those with less healthy diets, new research reveals, suggesting food choices in midlife may reduce the risk of dementia and other degenerative ...
Dec 15, 2021
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Growing evidence indicates that gut microbiota plays a critical role in regulating the progression of neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease (AD), but the molecular mechanism underlying ...
Sep 7, 2021
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Lafora disease is an inherited neurodegenerative condition that initially develops with seizures in adolescence and evolves with progressive degeneration of the nervous system to death, about ten years after its onset. It ...
Apr 20, 2021
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A recent study in Science Advances by researchers at Karolinska Institutet and Max Planck Institute, shows that neurons can counteract degeneration and promote survival by adapting their metabolism. It challenges the long-standing ...
Aug 31, 2020
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Alzheimer's disease (AD) is known to involve interactions among many different genes, making it difficult to pinpoint the specific mechanisms. But now, researchers from Japan have found a new way to identify genes implicated ...
Apr 14, 2020
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