An antibiotic, minocycline, can increase the lifespan of roundworms by preventing the build-up of proteins during aging, a study in the open-access journal eLife reports.
Nov 28, 2018
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Research from the University of Toronto has shown that in some neurodegenerative diseases, two hallmarks of cell aging – protein aggregation and a type of DNA instability – are linked. They were previously thought to ...
Nov 21, 2018
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Researchers at the Federal University of Rio de Janeiro (UFRJ) and the State University of Rio de Janeiro (UERJ) have made a discovery that could lead to the development of a treatment against more than half of breast cancer ...
Jun 27, 2018
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Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have characterized the mechanism that initiates the pathological aggregation of the protein FUS, which plays a central role in two distinct neurodegenerative diseases.
Apr 20, 2018
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A common thread ties seemingly unlinked disorders like Alzheimer's disease and type II diabetes together. This thread is known as protein aggregation and happens when proteins clump together. These complexes are a hallmark ...
Oct 22, 2017
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In a recent Frontiers in Aging Neuroscience paper, Drs. Della David and Frank Baumann together with their teams at the German Center for Neurodegenerative Diseases and Hertie Institute, showed that changes in proteins associated ...
May 17, 2017
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A vast class of incurable neurodegenerative disorders are characterized by the aggregation and deposition of aberrant proteins like the amyloid b peptide or a-synuclein, considered to be factors behind the development of ...
Sep 21, 2016
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Researchers from the Massachusetts Institute of Technology and Boston University have developed a system capable of quickly screening millions of yeast cells to measure protein aggregates. Proteins regulate all of the processes ...
Jul 13, 2016
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An innovative tool allows researchers to observe protein aggregation throughout the life of a worm. The development of these aggregates, which play a role in the onset of a number of neurodegenerative diseases, can now be ...
Feb 15, 2016
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The ALS-related protein TDP-43 takes the first steps toward pathologic aggregation as part of its normal function, according to a new study publishing in the Open Access journal PLOS Biology on Jan. 6, 2016. The study, by ...
Jan 6, 2016
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