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Research reveals possible reason for cholesterol-drug side effects

The U.S. Food and Drug Administration and physicians continue to document that some patients experience fuzzy thinking and memory loss while taking statins, a class of global top-selling cholesterol-lowering ...

Medical research created May 10, 2013 | popularity 4.4 / 5 (12) | comments 13 | with audio podcast

New research finds statins don't reduce skin cancer risk

(Medical Xpress) -- Murmurings over the past couple of years suggesting that certain statins might reduce the risk for people developing skin cancer, have proven to be unfounded. New research by a team working out of the ...

Cancer created Apr 23, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast report

Cardiovascular benefits of taking statins outweigh diabetes risk

The benefits of taking statins to reduce the risk of cardiovascular disease outweigh the increased risk of developing diabetes experienced by some patients who take these cholesterol-lowering drugs, according to an Article ...

Diabetes created Aug 09, 2012 | popularity 3 / 5 (4) | comments 1

New drug may help those who can't take statins

(HealthDay)—An experimental drug may help patients who can't tolerate statins lower their cholesterol, a new Australian study suggests.

Cardiology created Nov 05, 2012 | popularity 4 / 5 (3) | comments 0 | with audio podcast

Study finds statin costs 400 percent higher in US compared to UK

In the United States, the cost paid for statins (drugs to lower cholesterol) in people under the age of 65 who have private insurance is approximately 400 percent higher than comparable costs paid by the government in the ...

Medications created Jan 05, 2012 | popularity 3.7 / 5 (3) | comments 12

The cost of prescription drugs—a comparison of two countries

In the United States, the cost paid for statins (drugs to lower cholesterol) in people under the age of 65 who have private insurance continues to exceed comparable costs paid by the government in the United Kingdom (U.K.) ...

Medications created Nov 01, 2012 | popularity 3.7 / 5 (3) | comments 1

Study finds no link between statins and cancer risk

(Medical Xpress) -- A new study published in the Journal of the American College of Cardiology reports that, contrary to previous studies, the use of cholesterol reducing statin drugs does not increase the risk of patien ...

Cancer created Jul 25, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast report

Statins reduce deaths from infection and respiratory illness, eight years on from trial

The death rate among patients prescribed a statin in a major trial that ended in 2003 is still lower than those given a placebo, even though most participants in both groups have been taking statins ever since. ASCOT, the ...

Cardiology created Aug 28, 2011 | popularity 5 / 5 (2) | comments 0

Monthly shot lowers cholesterol 66 percent: study

A monthly injection of an experimental drug made by the US biotech firm Amgen reduced patients' cholesterol by up to 66 percent, according to a small study described at a US cardiology conference.

Cardiology created Mar 26, 2012 | popularity 5 / 5 (2) | comments 5

HDL: Not so 'good' after all?

After years of having it drilled into their heads, most people now know that LDL (low-density lipoprotein) is the "bad" cholesterol package that increases the risk of cardiovascular disease, and HDL (high-density ...

Health created Aug 28, 2012 | popularity 5 / 5 (2) | comments 0

New drug significantly lowers bad cholesterol

For many people with high cholesterol, statins serve as the first line of treatment. However, some patients are unable to effectively reduce their low-density lipoprotein cholesterol (LDL cholesterol) or "bad cholesterol" ...

Cardiology created Nov 06, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Cholesterol medicine affects energy production in muscles

Up to 75 per cent of patients who take statins to treat elevated cholesterol levels may suffer from muscle pain. Scientists at the Center for Healthy Aging at the University of Copenhagen have now identified ...

Cardiology created Jan 03, 2013 | popularity 5 / 5 (2) | comments 0

A new use for statins?

Older patients who happened to have been taking cholesterol-lowering statin drugs when admitted to the hospital with serious head injuries were 76 percent more likely to survive than those not taking the drugs, according ...

Medications created Oct 18, 2011 | popularity 4.5 / 5 (2) | comments 1

Statins are unlikely to prevent blood clots, analysis finds

Despite previous studies suggesting the contrary, statins (cholesterol-lowering drugs) may not prevent blood clots (venous thrombo-embolism) in adults, according to a large analysis by international researchers published ...

Cardiology created Sep 18, 2012 | popularity 3 / 5 (2) | comments 1 | with audio podcast

Intensive-dose statin therapy associated with increased risk of diabetes

An analysis of data from previously published studies indicates that intensive-dose statin therapy is associated with an increased risk of new-onset diabetes compared with moderate-dose therapy, according to a study in the ...

Diseases, Conditions, Syndromes created Jun 21, 2011 | popularity 5 / 5 (1) | comments 0

Statin

The statins (or HMG-CoA reductase inhibitors) are a class of drugs that lower cholesterol levels in people with or at risk of cardiovascular disease.

They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver results in decreased cholesterol synthesis as well as increased synthesis of LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream. The first results can be seen after one week of use and the effect is maximal after four to six weeks.

For more information about Statin, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: heart disease , drug , heart attack , cholesterol