Researchers at the Francis Crick Institute, working with Imperial College London, King's College London and University of Cambridge, have shown that an influx of water and ions into immune cells allows them to migrate to ...
Dec 6, 2023
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When Joanina Gicobi began her Ph.D. degree five years ago at Mayo Clinic Graduate School of Biomedical Sciences, she was interested in thinking creatively about ways to improve cancer treatment. In particular, she was curious ...
Dec 4, 2023
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Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for pediatric patients with relapsed and recurrent leukemia. However, these therapies are not as effective in treating ...
Nov 30, 2023
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A new paper in Science Advances details how scientists have succeeded in mapping a central part of the immune system—the HLA class II molecules—while accurately predicting how they display fragments of pathogens on the ...
Nov 27, 2023
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Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to ...
Nov 22, 2023
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Just as the body's immune system can fight off infection, it can be a powerful weapon against cancer. Harnessing and fine-tuning that weapon, however, will require a better understanding of the complex interactions between ...
Nov 22, 2023
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Findings from St. Jude Children's Research Hospital are moving the field of cancer immunotherapy one step closer to treating brain and solid tumors. Scientists at St. Jude validated a cellular immunotherapy target called ...
Nov 21, 2023
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A recent publication from Audrey Gérard's lab looks at how a specific protein, called IFNγ, can coordinate CD8+ T cell responses during a flu infection.
Nov 21, 2023
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T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known ...
Nov 15, 2023
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CAR T cell therapy, a powerful type of immunotherapy, has begun to revolutionize cancer treatment. Pioneered at Memorial Sloan Kettering Cancer Center (MSK), the therapy involves engineering a patient's T cells so they recognize ...
Nov 14, 2023
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