New monoclonal antibody inhibits tumor growth in advanced solid tumors in phase I clinical trial
A newly developed antibody targeting a signalling pathway that is frequently active in solid tumours has shown encouraging signs of efficacy in its first trial in humans, researchers will report at the 24th EORTC-NCI-AACR ...
Cancer
Nov 06, 2012 |
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Scientists test 5,000 combinations of 100 existing cancer drugs to find more effective treatments
Scientists in the United States have tested all possible pairings of the 100 cancer drugs approved for use in patients in order to discover whether there are any combinations not tried previously that are effective in certain ...
Cancer
Nov 06, 2012 |
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Novel cell growth factor for preventing and treating injury caused by high-level radiation exposure
Japanese researchers have created novel cell growth factor FGFC that is considered effective in preventing and treating injury due to high-dose radiation. Until now, there have been insufficient drugs effective ...
Medical research
Nov 02, 2012 |
5 / 5 (1) |
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Scientists identify new target for lung cancer treatment
A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed ...
Cancer
Nov 01, 2012 |
4 / 5 (1) |
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Research identifies new therapeutic target for Alzheimer's disease
Research led by Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans, has identified an enzyme called Monoacylglycerol lipase (MAGL) as a new therapeutic target to treat or prevent ...
Alzheimer's disease & dementia
Nov 01, 2012 |
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Recent findings may help to fight melanoma's resistance to chemotherapy
Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Instit ...
Cancer
Oct 31, 2012 |
1 / 5 (1) |
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New developments reveal a molecule with a promising function in terms of cancer treatment.
Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have focussed their efforts on ...
Cancer
Oct 30, 2012 |
5 / 5 (1) |
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Biomarkers of behavior, therapeutic targets for adult B-acute lymphoblastic leukemia identified
New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target.
Cancer
Oct 29, 2012 |
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Scientists identify progenitor cells, potential new 'roots' of breast cancer
Scientists have discovered new types of early cells in mammary glands, uncovering clues to the origins of different breast cancers - and potential new drug targets, according to findings published in Breast Ca ...
Cancer
Oct 29, 2012 |
2 / 5 (1) |
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Study finds diabetes raises levels of proteins linked to Alzheimer's features
Growing evidence suggests that there may be a link between diabetes and Alzheimer's disease, but the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. ...
Alzheimer's disease & dementia
Oct 26, 2012 |
5 / 5 (1) |
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New target for treating diabetic kidney disease, the leading cause of kidney failure
Researchers have discovered a new therapeutic target for diabetic nephropathy, the leading cause of kidney failure. The findings, appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN) ...
Diseases, Conditions, Syndromes
Oct 18, 2012 |
5 / 5 (1) |
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Researchers elucidate transport pathway of immune system substances
To transport substances from the site of their production to their destination, the body needs a sophisticated transport and sorting system. Various receptors in and on the cells recognize certain molecules, pack them and ...
Immunology
Oct 18, 2012 |
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Cold viruses point the way to new cancer therapies
Cold viruses generally get a bad rap—which they've certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ...
Cancer
Oct 16, 2012 |
5 / 5 (5) |
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Finding the origins of infant leukaemia
Leukaemia arises as a result of genetic or epigenetic alterations in blood cells, leading to an aberrant accumulation of undifferentiated blasts. Understanding the molecular pathogenesis and aetiology of ...
Cancer
Oct 15, 2012 |
5 / 5 (1) |
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New study to combat the most common form of liver cancer
Scientists at the University of Southampton are to investigate the best way to use natural killer cells (NK) to target the most common form of liver cancer.
Cancer
Oct 12, 2012 |
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