A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that ...
Mar 28, 2023
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104
An estimated 15 to 20 percent of all breast cancer patients are "triple negative." These unfortunate women lack three crucial treatment targets—the estrogen receptor, the progesterone receptor and human epidermal growth ...
Mar 6, 2019
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116
It is estimated that during a heart attack, one billion cells in the heart are lost. In the wake of the heart attack, the lost tissue is replaced by scar tissue, which can lead to heart failure, arrhythmia and death. In a ...
Jun 2, 2021
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Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the ...
Jul 30, 2015
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When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas ...
Jan 27, 2012
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Two types of cells are active in the brain: nerve cells and glial cells. Glial cells have long been regarded primarily as supportive cells, but researchers increasingly recognize that they play an active role in the communication ...
Dec 11, 2018
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Dramatic expansion of the human cerebral cortex, over the course of evolution, accommodated new areas for specialized cognitive function, including language. Understanding the genetic mechanisms underlying these changes, ...
Nov 9, 2012
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A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a chemical "switch" that controls both the generation of new neurons from neural stem cells and the survival of existing ...
Jul 3, 2014
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Pancreatic cancer is the No. 3 cause of cancer-related deaths in the United States, and only 12% of patients survive five years after being diagnosed. Severe pancreatic cancer is associated with metastasis, and it is this ...
Feb 3, 2024
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59
Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.
Jun 3, 2020
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