Experimental drug beneficial in NIH trial to treat a rare sarcoma
(Medical Xpress)—Patients with advanced alveolar soft part sarcoma (ASPS), a rare cancer, achieved some control of their disease using an experimental anti-cancer drug called cediranib. The results from ...
Cancer
May 07, 2013 |
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Decoded: Molecular messages that tell prostate and breast cancers to spread
Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain ...
Cancer
Apr 30, 2013 |
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Two-drug combo more effective in treating sarcomas, study shows
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors. They report ...
Cancer
Apr 09, 2013 |
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Brain-building gene plays key role in gut repair
(Medical Xpress)—A gene with a colorful name – mindbomb 1 – plays a key role far beyond the brain. New research at Washington University School of Medicine in St. Louis shows that mindbomb 1 may be ...
Genetics
Apr 05, 2013 |
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Genetic vulnerability of lung cancer to lay foundation for new drug options
Physician-researchers at UT Southwestern Medical Center have identified a vulnerability of certain lung-cancer cells – a specific genetic weakness that can be exploited for new therapies.
Cancer
Apr 04, 2013 |
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Newly identified tumor suppressor provides therapeutic target for prostate cancer
Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCζ suppresses prostate tumor formation. The finding, which also describes a molecular chain ...
Cancer
Apr 01, 2013 |
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Storming the gates: Study probes how pancreatic cancers metastasize
Researchers at the University of North Carolina at Chapel Hill have discovered that a protein found in the cells surrounding pancreatic cancers play a role in the spread of the disease to other parts of the ...
Cancer
Mar 25, 2013 |
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New epigenetic mechanisms for improved cancer therapy
A review article by researchers at Boston University School of Medicine (BUSM) proposes a new epigenetic hypothesis linked to tumor production and novel ideas about what causes progenitor cells to develop into cancer cells. ...
Cancer
Feb 19, 2013 |
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Protein that represses critical checkpoint protein for cellular growth helps drive tumor development
(Medical Xpress)—One of the hallmarks of cancer is unchecked cellular growth. Fortunately, our cells contain a number of tumor suppressor proteins, including the cell cycle regulator p21, to keep cell growth ...
Cancer
Feb 13, 2013 |
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Genetic landscape of common brain tumors holds key to personalized treatment
Nearly the entire genetic landscape of the most common form of brain tumor can be explained by abnormalities in just five genes, an international team of researchers led by Yale School of Medicine scientists report online ...
Cancer
Jan 24, 2013 |
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Scientists use luminescent mice to track cancer and aging in real-time
In a study published in the January 18 issue of Cell, researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have developed a new method to visualize aging and tumor growth ...
Medical research
Jan 17, 2013 |
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Lack of protein Sp2 disrupts neuron creation in brain
(Medical Xpress)—A protein known as Sp2 is key to the proper creation of neurons from stem cells, according to researchers at North Carolina State University. Understanding how this protein works could ...
Neuroscience
Jan 14, 2013 |
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Researchers discover novel role of the NEDD9 gene in early stages of breast cancer
Breast cancer is the second leading cause of cancer deaths among women in the United States. Many of these deaths occur when there is an initial diagnosis of invasive or metastatic disease. A protein called NEDD9—which ...
Cancer
Jan 14, 2013 |
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Spread of cancer cells may be slowed by targeting of protein
(Medical Xpress)—The spread of cancer cells may be slowed by targeting the protein km23-1, according to researchers at Penn State College of Medicine.
Cancer
Dec 18, 2012 |
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Study unmasks regulator of healthy life span
A new series of studies in mouse models by Mayo Clinic researchers uncovered that the aging process is characterized by high rates of whole-chromosome losses and gains in various organs, including heart, muscle, kidney and ...
Medical research
Dec 17, 2012 |
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