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Archive
11/12/2023

Archive: 11/12/2023

Revolutionizing probiotic therapy: The emergence of CRISPR-Cas engineered strains

Probiotics, defined as live microorganisms beneficial to health, have shown promise in areas like anti-inflammatory activity and brain function, etc. However, challenges remain due to variability in tolerance and colonization ...

Dec 11, 2023

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Landscape for acute myeloid leukemia patients evolving rapidly as research discoveries advance new treatments

The treatment landscape for acute myeloid leukemia (AML) is evolving rapidly, as research discoveries at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and other academic cancer ...

Dec 11, 2023

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Novel menin inhibitors show promise for patients with advanced acute myeloid leukemias

Two clinical trials led by researchers from The University of Texas MD Anderson Cancer Center demonstrated early positive results from novel therapies targeting menin for the treatment of relapsed or refractory acute leukemias ...

Dec 11, 2023

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42

Trust issues prevent sharing of vital health and welfare data in Australia, finds study

A lack of trust between institutions in Australia is a bigger hurdle to the easy sharing of health and social welfare data than perceived state legislation obstacles—which researchers say largely don't have a detrimental ...

Dec 11, 2023

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Pharmacologic restraint used in 3 percent of pediatric mental health admissions

The use of pharmacologic restraints occurs in 3 percent of hospitalizations for children admitted with a primary mental health diagnosis, according to a study published online Dec. 11 in Pediatrics.

Dec 11, 2023

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Targeted oral therapy reduces disease burden and improves symptoms for patients with rare blood disorder in trial

The targeted therapy bezuclastinib was safe and rapidly reduced markers of disease burden while also improving symptoms for patients with a rare blood disorder called nonadvanced system mastocytosis, according to results ...

Dec 11, 2023

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Novel combination therapy found to significantly reduce spleen volume in patients with myelofibrosis

Combining the JAK inhibitor ruxolitinib with the BCL-xL inhibitor navitoclax was twice as effective in reducing enlarged spleens—a major indicator of clinical improvement—compared with standard-of-care ruxolitinib monotherapy ...

Dec 11, 2023

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The relationship between health and structural racial discrimination

In celebrating its 75th anniversary, the World Health Organization has recently called for a renewed drive for health equity—that is, the opportunity for everyone to achieve an optimal health status.

Dec 11, 2023

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Alzheimer's in one sibling raises risk of shortened lifespan in others

An Alzheimer's diagnosis in a sibling raises the risk of a shortened lifespan in other family members—even those without dementia, according to new USC research based on data from the Swedish Twin Registry.

Dec 11, 2023

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Long-term results show combination treatment that skips chemotherapy is effective for older patients with Ph+ ALL

Older patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) who were not good candidates for the standard treatment of intensive chemotherapy had a median overall survival (OS) of 6.5 years ...

Dec 11, 2023

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