Archive: 16/04/2018
An off-the-shelf, dual-targeted CAR T-cell product shows promising results in preclinical studies
FT819, an off-the-shelf, T-cell receptor (TCR)-less CD19 CAR T-cell product that could potentially be made more accessible to cancer patients than conventional CAR T-cell therapies showed positive results in preclinical specificity, ...
Apr 16, 2018
Expansion of circulating tumor-specific T cells after treatment suggested systemic antitumor immunity
The anti-PD1 immunotherapy nivolumab (Opdivo) given prior to surgical resection of stage 1-3 non-small cell lung cancer (NSCLC) was safe and resulted in major pathological responses in 45 percent of the patients, according ...
Apr 16, 2018
Selective inhibitor shows early promise in patients with RET-altered cancers
BLU-667, a next-generation inhibitor that selectively targets the oncogenic receptor tyrosine kinase RET, was well tolerated and had broad clinical benefit in patients with advanced cancer that had progressed on previous ...
Apr 16, 2018
Children with non-chromosomal birth defects face higher risk of several childhood cancers
Children with non-chromosomal birth defects such as congenital heart disease had a significantly higher risk of developing childhood cancer than children who did not have birth defects, according to a study presented at the ...
Apr 16, 2018
Saffron spices up mental health research
Murdoch University researcher Dr. Adrian Lopresti saw promising results studying saffron as a treatment for depression and anxiety in adolescents.
Apr 16, 2018