Archive: 23/04/2019

FDA approves pembrolizumab plus axitinib for advanced RCC

(HealthDay)—The combination of pembrolizumab and axitinib has been approved as a first-line treatment in advanced renal cell carcinoma (RCC), the U.S. Food and Drug Administration announced Friday.

Apr 23, 2019

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With humor—and brain-shaped Jell-O—this doctor teaches kids about health

One of the most valuable lessons in pediatrician April Inniss' medical career came from an 8-year-old boy.

Apr 23, 2019

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In severe, asymptomatic aortic stenosis, early surgery may help

(HealthDay)—Early aortic valve replacement (AVR) may improve survival in patients with severe, asymptomatic aortic stenosis, according to a study published online March 20 in The Annals of Thoracic Surgery.

Apr 23, 2019

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Shining light on rare nerve tumors illuminates a fresh path for fighting cancer

When a protein named "Merlin" fails to do its job, people can develop slow-growing, life-disrupting auditory nerve tumors that can disrupt their hearing and balance. This rare condition is called neurofibromatosis 2 (NF2).

Apr 23, 2019

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Low socioeconomic position associated with worse care at the end of life

In high-income countries, people with low socioeconomic position are more likely to receive poor quality end of life care and die in hospital, according to a large meta-analysis by Joanna Davies of King's College London, ...

Apr 23, 2019

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Texting to improve health outcomes for people with schizophrenia

Texting patients with schizophrenia and their lay health supporters in a resource-poor community setting is more effective than a free-medicine program alone in improving medication adherence and reducing relapses and re-hospitalizations, ...

Apr 23, 2019

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Calcium deficiency in cells due to ORAI1 gene mutation leads to damaged tooth enamel

A mutation in the ORAI1 gene—studied in a human patient and mice—leads to a loss of calcium in enamel cells and results in defective dental enamel mineralization, finds a study led by researchers at NYU College of Dentistry.

Apr 23, 2019

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Researchers devise a progression risk-based classification for patients with AWM

By analyzing data from hundreds of patients with asymptomatic Waldenström macroglobulinemia (AWM), researchers at Dana-Farber Cancer Institute have devised a risk model for determining whether patients with AWM have a low, ...

Apr 23, 2019

When designing clinical trials for Huntington's disease, first ask the experts

Progress in understanding the genetic mutation responsible for Huntington's disease (HD) and at least some molecular underpinnings of the disease has resulted in a new era of clinical testing of potential treatments. How ...

Apr 23, 2019

When is sexting associated with psychological distress among young adults?

While sending or receiving nude electronic images may not always be associated with poorer mental health, being coerced to do so and receiving unwanted sexts was linked to a higher likelihood of depression, anxiety, and stress ...

Apr 23, 2019

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