Archive: 24/04/2014

Fruit fly study identifies brain circuit that drives daily cycles of rest, activity

Amita Sehgal, PhD, a professor of Neuroscience at the Perelman School of Medicine, University of Pennsylvania, describes in Cell a circuit in the brain of fruit flies that controls their daily, rhythmic behavior of rest and ...

Apr 24, 2014

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Scientists find way to target cells resistant to chemo

Scientists from The University of Manchester have identified a way to sensitise cancer cells to chemotherapy - making them more open to treatment.

Apr 24, 2014

Surprising new insights into the PTEN tumor suppressor gene

Ever since it was first identified more than 15 years ago, the PTEN gene has been known to play an integral role in preventing the onset and progression of numerous cancers. Consequently, when PTEN is either lost or mutated, ...

Apr 24, 2014

Oops! Researchers find neural signature for mistake correction

Culminating an 8 year search, scientists at the RIKEN-MIT Center for Neural Circuit Genetics captured an elusive brain signal underlying memory transfer and, in doing so, pinpointed the first neural circuit for "oops" ? the ...

Apr 24, 2014

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Researchers discover new genetic brain disorder in humans

A newly identified genetic disorder associated with degeneration of the central and peripheral nervous systems in humans, along with the genetic cause, is reported in the April 24, 2014 issue of Cell.

Apr 24, 2014

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Team reprograms blood cells into blood stem cells in mice

Researchers at Boston Children's Hospital have reprogrammed mature blood cells from mice into blood-forming hematopoietic stem cells (HSCs), using a cocktail of eight genetic switches called transcription factors. The reprogrammed ...

Apr 24, 2014

Researchers create comprehensive map of human B cell development

In the April 24, 2014 edition of Cell, a team of researchers led by Dana Pe'er at Columbia University and Garry Nolan at Stanford University describes a powerful new method for mapping cellular development at the single cell ...

Apr 24, 2014

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Skin layer grown from human stem cells could replace animals in drug and cosmetics testing

An international team led by King's College London and the San Francisco Veteran Affairs Medical Center (SFVAMC) has developed the first lab-grown epidermis – the outermost skin layer - with a functional permeability barrier ...

Apr 24, 2014