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28/05/2020

Archive: 28/05/2020

Combination therapy well-tolerated and highly effective for patients with IDH1-mutated AML

A combination therapy of ivosenidib (IVO) plus venetoclax (VEN) with or without azacitidine (AZA) was found to be effective against a specific genetic subtype of acute myeloid leukemia (AML) in a Phase Ib/II trial led by ...

May 28, 2020

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8

Study shows uptick in at-home pediatric fractures during COVID-19 pandemic

COVID-19 social distancing measures, including the closure of schools and parks and the indefinite cancelation of team sports, have led to a nearly 60% decrease overall in pediatric fractures but an increase in the proportion ...

May 28, 2020

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3

Novel targeted drug induced positive response for VHL-associated kidney cancer

In an international trial led by researchers at The University of Texas MD Anderson Cancer Center, treatment with MK-6482, the small molecule inhibitor of hypoxia-inducible factor (HIF)-2a was well tolerated and resulted ...

May 28, 2020

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1

Cancer doctors call for more training in palliative care and delivery of 'bad news'

Oncologists who practice and teach at the Johns Hopkins Kimmel Cancer Center are calling on medical oncology training programs to invest substantially more time educating physicians about palliative care and how to talk to ...

May 28, 2020

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2

Colorado tool, My-DST, may pick best multiple myeloma treatment

In 1844, multiple myeloma was first treated with a rhubarb pill and an infusion of orange peel. Since then, more than 15 drugs have earned FDA approval to treat multiple myeloma and with so many options, a major question ...

May 28, 2020

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3

New drug combinations help overcome resistance to immunotherapy

A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations ...

May 28, 2020

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1

Survey identifies learning opportunities related to health impacts of climate change

An international survey of Global Consortium on Climate and Health Education (GCCHE) membership found that the majority of members—health professions schools and programs, including medical, nursing, and public health—offer ...

May 28, 2020

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2

Restoring nerve-muscle communication in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles. Previous ...

May 28, 2020

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28

Mapping immune cells in brain tumors

The removal of a malignant brain tumor is something of a balancing act between removing as much tumor tissue as possible at the same time as protecting the healthy tissue. Since cancer cells infiltrate healthy brain tissue, ...

May 28, 2020

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62

Researchers track new path to therapeutic prevention of abdominal aortic aneurysm

The main thoroughfare that carries oxygen-rich blood from the heart to the abdomen is known as the abdominal aorta. Strong and thick-walled, this main highway is built to withstand a lifetime of use. But just like expressways ...

May 28, 2020

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