Children with relapsed or refractory malignant rhabdoid tumors, epithelioid sarcomas, or poorly differentiated chordomas with a particular genetic defect tolerated treatment with the investigational drug tazemetostat well ...
Oct 30, 2017
The number of early-phase trials in oncology that adopted a seamless approach, as opposed to a traditional trial approach with defined phase I, II, and III plans, is rising, with data from the majority of them presented after ...
Oct 30, 2017
At the RIKEN Brain Science Institute in Japan, a two-year project from Andrea Benucci's research group has culminated in the construction and deployment of a high-throughput system to study mouse behavior and physiology. ...
Oct 30, 2017
Whole exome sequencing revealed that colorectal cancers with high mutational load (MSI-H) predominantly use "immunoediting" to escape immune surveillance while colorectal cancers with low mutational load (MSS) use oncogenic ...
Oct 30, 2017
A computational imaging-based signature of immune-cell infiltration in and around a tumor could predict patients' responses to treatment with anti-PD1/PDL1 immunotherapies, according to data from a study presented at the ...
Oct 30, 2017
