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Archive
09/04/2024

Archive: 09/04/2024

AZD1390 with radiotherapy shows manageable safety profile and preliminary efficacy for patients with glioblastoma

AZD1390, an ataxia telangiectasia mutant (ATM) kinase inhibitor, demonstrated a manageable safety profile in both recurrent and newly diagnosed glioblastoma (GBM) patients when given in combination with standard-of-care radiotherapy ...

Apr 9, 2024

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Some proteogenomic signatures linked to prostate cancer progression in patients with African and European ancestries

Certain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated with higher risk of metastasis and/or recurrence of the disease, according to a study presented at the American ...

Apr 9, 2024

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Myths about PSA tests and prostate cancer screening

The understanding of prostate cancer has significantly evolved in the past 15 years. However, many people—including primary care providers—may not be aware of the current guidelines for prostate cancer screening, says ...

Apr 9, 2024

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4

Researchers call for focus on higher stroke risk in women

While stroke is the fifth-leading cause of death for men, it's the third-leading cause of death for women in the United States.

Apr 9, 2024

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CMS121 mitigates aging-related obesity and metabolic dysfunction: Study

A new research paper titled "CMS121: a novel approach to mitigate aging-related obesity and metabolic dysfunction" has been published in Aging.

Apr 9, 2024

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How cellular plasticity drives cancer metastasis

About 90% of deaths from cancer are a result of metastasis—that is, from cancer's ability to spread from an initial primary tumor to seed new tumors throughout the body, often in the lungs, liver, and brain.

Apr 9, 2024

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Cognitive decline may be detected using network analysis, according to researchers

We all lose our car keys or our glasses from time to time. Most people would be correct to laugh it off as a normal part of aging. But for others, cognitive decline may start as a worrying but clinically unnoticeable step ...

Apr 9, 2024

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3

Unlocking the body's hidden weapon against cancer: The role of broken chromosomes

Scientists have unraveled the mechanisms of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) signaling pathway activated by micronuclei, as well as its significant ...

Apr 9, 2024

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Morphine tolerance found to result from Tiam1-mediated maladaptive plasticity in spinal neurons

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems—prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, ...

Apr 9, 2024

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53

EPA cracks down on toxins threatening those living near chemical plants

Are you one of the estimated 104,000 Americans who lives within six miles of factories that spew organic chemicals into the air?

Apr 9, 2024

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