New technique that makes competition between tumor cells visible can help personalize treatments for multiple myeloma
Not all cells within the same cancer are the same. They all have genetic errors that turn them into tumor cells, but these errors are not identical. In each cancer, there are populations of cells with different mutations, ...
15 hours ago
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Failure in a CAR T cell trial could unlock multiple treatments for acute myeloid leukemia
In the clinical battle against leukemia, recent breakthroughs in chimeric antigen receptor T cells (CAR T) have given patients and doctors an unprecedented weapon. CAR T cell therapy has demonstrated efficacy in treating ...
Significant worldwide disparities seen in availability and timeliness of new cancer drugs
Despite considerable progress in the discovery and development of new cancer drugs, there are significant disparities in both the availability and timeliness of these medicines worldwide, with poorer countries missing out, ...
11 hours ago
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Cell line models identify cause of melanoma with drug resistance
Melanoma is a type of cancer that originates from melanocytes, the cells responsible for producing skin pigment, and is known as the most lethal form of skin cancer due to its high rates of metastasis and recurrence. With ...
16 hours ago
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Mouse model suggests bacterial-derived metabolites may promote prostate cancer
Every year, over 1.5 million new cases of prostate cancer are diagnosed throughout the world. As one of the leading causes of death for men in multiple countries, understanding the risk factors for prostate cancer has become ...
20 hours ago
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AI could help identify women at risk for future breast cancer
Artificial intelligence (AI) scores may be able to estimate the risk for future breast cancer and lead to earlier diagnosis, according to a study published online Oct. 3 in JAMA Network Open.
13 hours ago
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Prostate cancer Q&A: Improving detection and reducing overtreatment
Prostate cancer is the most common cancer among men in Sweden, with about 10,000 new cases diagnosed annually. Despite advancements in diagnostics and treatments, managing prostate cancer remains challenging due to its often ...
15 hours ago
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Researchers reveal rare neurological symptoms in youth following CAR-T therapy
Researchers at Children's Hospital of Philadelphia (CHOP) revealed for the first time that children, adolescents and young adults may experience very rare neurological issues of paraparesis and quadriparesis following chimeric ...
17 hours ago
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Harnessing natural killer T cells to advance cancer immunotherapy for solid tumors
In the fight against cancer, chimeric antigen receptor T cell (CAR-T) therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.
Oct 7, 2024
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Scientists discover that special immune cells stop metastatic cancer
Metastatic disease—when cancer spreads from the primary tumor to other parts of the body—is the cause of most cancer deaths. While researchers understand how cancer cells escape the primary site to seed new tumors, it's ...
Oct 7, 2024
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AI model shows potential for identifying sex-specific risks associated with brain tumors
For years, cancer researchers have noticed that more men than women get a lethal form of brain cancer called glioblastoma. They've also found that these tumors are often more aggressive in men. But pinpointing the characteristics ...
Oct 7, 2024
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Epigenetic test could help predict efficacy of immunotherapy in multiple myeloma
Multiple myeloma is a type of blood cancer that appears mainly after the age of 60. Its incidence, therefore, increases with the aging of the population. In this pathology, the bone marrow, the porous structure within the ...
Oct 7, 2024
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Early blood test can predict survival in men newly diagnosed with metastatic prostate cancer, clinical trial finds
A blood test, performed when metastatic prostate cancer is first diagnosed, can predict which patients are likely to respond to treatment and survive the longest. It can help providers decide which patients should receive ...
Oct 7, 2024
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Cancer biologists discover the drug, 5-fluorouracil, acts differently in different types of cancer
Since the 1950s, a chemotherapy drug known as 5-fluorouracil has been used to treat many types of cancer, including blood cancers and cancers of the digestive tract.
Oct 7, 2024
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Promising cell therapy offers hope for relapsed or refractory T-cell leukemia
A new cell therapy, targeting CD7 in leukemia cells, gives a potentially effective treatment for patients with T-cell acute lymphoblastic leukemia (T-ALL) who have exhausted all standard treatment options. Published in the ...
Oct 7, 2024
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Discovery of key gene offers new hope in treating chronic myeloid leukemia
A key gene that could enhance the treatment success rates of chronic myeloid leukemia (CML) has been discovered by researchers.
Oct 7, 2024
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Study shows cancer vaccine blocks tumor progression at early lesion stage
A cancer vaccine that had little success in clinical trials for patients with advanced tumors could potentially have efficacy if administered earlier in the treatment cycle, according to a study from Vanderbilt researchers.
Oct 7, 2024
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Study finds common breast cancer treatments may speed aging process
A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center has revealed that common breast cancer treatments, including chemotherapy, radiation, and surgery, may accelerate the biological aging ...
Oct 7, 2024
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New immunotherapy shows complete responses in mantle cell lymphoma
Patients with a rare blood cancer that has relapsed or become resistant to treatment have shown a high response rate to a potent new immunotherapy drug, in a Peter Mac-led clinical trial.
Oct 7, 2024
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Study explores novel therapeutic treatment for glioblastoma
Glioblastoma (GBM) is the most lethal brain tumor, with a median survival rate of merely 12-16 months after diagnosis. Despite surgical, radiation and chemotherapy treatments, the two-year survival rate for GBM patients is ...
Oct 7, 2024
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Updated findings provide insights into radiation exposure's impact on cancer risk
A major update was made to the International Nuclear Workers Study (INWORKS), an international epidemiological study of workers in the nuclear sector to assess their risks of cancer and non-cancerous diseases.
Oct 7, 2024
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Analysis reveals improved cancer survival for young adults after passage of Affordable Care Act
The federal Patient Protection and Affordable Care Act (ACA) passed in 2010 includes a Dependent Coverage Expansion (DCE) provision that permits dependents to remain on their parents' health insurance plans from age 19 to ...
Oct 7, 2024
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Personalized radiotherapy for people with bladder cancer shows promise
Researchers are a step closer to revolutionizing how doctors use radiotherapy to treat patients with muscle-invasive bladder cancer.
Oct 7, 2024
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