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Oncology & Cancer news

Medical research

Molecular tumor boards improve identification of cancer-linked genes

Results from a new University of Kentucky Markey Cancer Center study show that molecular tumor boards can play an important role in identifying potential inherited cancer risks, leading to better patient care.

Oncology & Cancer

Disparities found for Non-Hispanic Black patients in hematopoietic cell transplantation use for hematologic cancers

Non-Hispanic Black patients in the United States appear to have persistent disparities in terms of hematopoietic cell transplantation (HCT) for various hematologic cancers, according to a study published online Sept. 18 in ...

Oncology & Cancer

Genetic mutations in HRAS, KRAS genes linked to childhood cancers

Hereditary changes in genes are often the cause of rare diseases. For example, disease-causing gene variants (PVs) in the HRAS gene cause Costello syndrome and PVs in the KRAS gene cause Noonan syndrome and cardio-facio-cutaneous ...

Oncology & Cancer

Saving time with AI-generated treatment plans for breast cancer

Drawing in the organs of individual breast cancer patients and then creating precise radiation plans appears to be faster by using artificial intelligence (AI) models. That way, it remains just as reliable and accurate. It ...

Oncology & Cancer

Treatment-free remission for chronic myeloid leukemia

Leukemias are cancers of the blood cells. Chronic myelogenous leukemia (CML) is an uncommon type of cancer of the bone marrow, which produces blood cells. "Myelogenous" refers to the type of blood cells this leukemia affects. ...

Oncology & Cancer

AI could predict breast cancer risk via 'zombie cells'

Women worldwide could see better treatment with new AI technology, which enables better detection of damaged cells and more precisely predicts the risk of getting breast cancer, shows new research from the University of Copenhagen.

Medical research

Promising drug combo targets aggressive bladder cancers

A new study in mice by researchers at the Herbert Irving Comprehensive Cancer Center (HICCC) has identified a promising drug combination for the treatment of muscle-invasive bladder cancer. Rosiglitazone plus trametinib worked ...

Oncology & Cancer

Analytical tool quantifies cancer's ability to shape-shift

A powerful new analytical tool offers a closer look at how tumor cells "shape-shift" to become more aggressive and untreatable, as shown in a study by researchers at Weill Cornell Medicine and the New York Genome Center.

Oncology & Cancer

Feedback loop promotes cancer cells' adaption to molecular stress

Investigators from the laboratory of Marc Mendillo, Ph.D., associate professor of Biochemistry and Molecular Genetics, have discovered new cellular regulators of a cancer cell transcription factor linked to cancer resilience ...

Oncology & Cancer

Retrotransposon DNA zip code for myeloma cell internalization

The complex interplay between extracellular genetic material and the tumor's genetic landscape presents a significant challenge in grasping cancer evolution, tumor genetic heterogeneity, and treatment response. Earlier research ...

Oncology & Cancer

Cannabis use tied to head and neck cancer

A study from the USC Head and Neck Center, part of Keck Medicine of USC and the USC Caruso Department of Otolaryngology—Head and Neck Surgery, suggests that cannabis, the most commonly used illicit substance worldwide, ...

Medical research

Newly discovered mechanism halts tumor cell replication

A research group at the University of Bologna has identified, for the first time, the specific location and genomic context where DNA breaks occur due to the inhibition of the topoisomerase I, a protein crucial for many biological ...

Medications

FDA approves Darzalex Faspro for treating multiple myeloma

The U.S. Food and Drug Administration has approved Johnson & Johnson's Darzalex Faspro (daratumumab and hyaluronidase-fihj) in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for induction and consolidation ...