Scientists reveal genetic drivers of metastasis across multiple cancer types
Cancer metastasis—the spread of cancer to other organs—is the leading cause of death among cancer patients. Researchers have now uncovered a "genetic signature" of 177 genes shared across multiple cancer types that drives ...
18 hours ago
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Combination treatment for liver cancer significantly improves progression-free survival in global trial
Researchers at Mount Sinai have made a breakthrough in treating a type of liver cancer called hepatocellular carcinoma (HCC). This research, led by Josep M. Llovet, MD, Ph.D., Professor of Medicine (Liver Diseases) at the ...
17 hours ago
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Drug resistance study reveals mechanisms that enable lung cancer recurrence
A recent study uncovers how drug-resistant cancer cells induce changes in the tumor microenvironment. This phenomenon promotes cancer recurrence and explains why initially effective targeted therapies can lose their efficacy ...
17 hours ago
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ORACLE lung cancer test predicts survival in early stages better than current methods
Researchers at the Francis Crick Institute, the UCL Cancer Institute and UCLH have shown that a test called ORACLE can predict lung cancer survival at the point of diagnosis better than currently used clinical risk factors. ...
23 hours ago
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AI platform identifies which patients are likely to benefit most from a cancer clinical trial
A study led by Winship Cancer Institute of Emory University and Abramson Cancer Center of the University of Pennsylvania researchers demonstrates that a first-of-its-kind platform using artificial intelligence (AI) could ...
23 hours ago
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Clinical trial shows 'Shared Care' model safe for patients after donor stem cell transplant
Patients undergoing a donor stem-cell transplant for leukemia or other blood-related cancer require months of specialized follow-up care, traditionally delivered at the center where they received their transplant—often ...
17 hours ago
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Transplant of frozen testicular tissue after chemotherapy during childhood provides hope for fertility restoration
In boys who, before starting puberty, undergo radical treatments that can affect their fertility, testicular tissue can be preventively removed and frozen. This is done to preserve testicular stem cells, the precursors of ...
21 hours ago
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Nonadherence to cancer screening varies by screening type
Nonadherence to cancer screening varies by screening type and sex, according to a study published in JAMA Network Open.
16 hours ago
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Talquetamab plus teclistamab shows promise in multiple myeloma
For patients with relapsed or refractory multiple myeloma, talquetamab plus teclistamab shows response in a high percentage of patients and a higher incidence of grade 3 or 4 infections than with either therapy alone, according ...
16 hours ago
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New tool puts reproductive risk for BRCA carriers into perspective
"I just wish someone had told me this was a possibility." Kara Maxwell distinctly remembers the moment she heard those words eight years ago from the mother of a child with Fanconi anemia (FA). Maxwell met her at a conference ...
19 hours ago
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Study identifies TBK1 as key to overcoming CAR T resistance
Russell W. Jenkins, MD, Ph.D., a physician investigator in the Krantz Family Center for Cancer Research at the Mass General Cancer Center and an assistant professor of Medicine at Harvard Medical School, is senior author ...
21 hours ago
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Improving cancer risk assessment and patient care: Researchers resolve uncertainty in BRCA2 testing
Findings from a multi-institutional, international study led by researchers from the Mayo Clinic Comprehensive Cancer Center have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player ...
Jan 8, 2025
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Unique AI predicts cancer prognoses and responses to treatment by combining data from medical images with text
The melding of visual information (microscopic and X-ray images, CT and MRI scans, for example) with text (exam notes, communications between physicians of varying specialties) is a key component of cancer care. But while ...
Jan 8, 2025
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AI-guided endoscope offers real-time precision during cancer surgery
An interdisciplinary research team in Jena, Germany, has developed an innovative endoscope that can precisely identify and selectively remove tumor tissue in real time during surgery.
Jan 8, 2025
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The same gene can drive distinct medulloblastoma types in different ways
A study published in Nature Genetics reveals new insights into how medulloblastoma, the most common malignant brain tumor of childhood, can arise as the cerebellum develops.
Jan 8, 2025
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Tracking the metabolic origins of cancer from a mosaic of cells
Yale researchers are sifting through a mosaic of cells in a living animal—both normal cells and mutated cells—to better understand how cancer grabs a foothold. But they're starting by studying tolerance.
Jan 8, 2025
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Tumor-secreted protein may hold the key to better treatments for deadly brain tumor
A study co-led by UCLA scientists has found targeting a protein called endocan and its related signaling pathway could be a promising new approach for treating glioblastoma, an aggressive and lethal type of brain cancer.
Jan 8, 2025
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Macrophages, not T cells, may hold key to predicting which melanoma patients are more likely to respond to immunotherapy
An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that engulf pathogens and cancer cells—can be used to predict whether or not a melanoma patient ...
Jan 8, 2025
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Using AI to predict the outcome of aggressive skin cancers
Artificial intelligence can determine the course and severity of aggressive skin cancers, such as Merkel cell carcinoma (MCC), to enhance clinical decision making by generating personalized predictions of treatment-specific ...
Jan 8, 2025
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End-of-life care can be more aggressive for cancer patients with defibrillators
Patients with advanced cancer who also had cardiac defibrillators were more likely than those without these implants to receive aggressive end-of-life care, a team led by UT Southwestern Medical Center researchers found in ...
Jan 8, 2025
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Understanding survival disparities in cancer care: A population-based study on mobility patterns
A study published in Health Data Science reveals significant survival disparities among cancer patients depending on their mobility patterns for medical care.
Jan 8, 2025
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Disparities in 36 cancers across 185 countries, says secondary analysis of global cancer statistics
Cancer remains a significant public health challenge, with the GLOBOCAN 2020 report estimating a staggering 19.3 million new cancer cases and 10 million cancer-related deaths globally. This burden is anticipated to escalate ...
Jan 8, 2025
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New AI tool uses routine blood tests to predict immunotherapy response for many cancers
Doctors around the world may soon have access to a new tool that could better predict whether individual cancer patients will benefit from immune checkpoint inhibitors—a type of immunotherapy—using only routine blood ...
Jan 7, 2025
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