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Oncology & Cancer news
Oncology & Cancer
Engineered dendritic cells boost cancer immunotherapy
EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy.
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Oncology & Cancer
WISDOM trial weighs risk-based cancer screening
University of California, San Francisco investigators led WISDOM, a randomized comparison of risk-based breast cancer screening and annual mammography. Rates of stage ≥IIB breast cancers met a noninferiority threshold under ...
15 hours ago
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RNA-based molecule enhances therapies against pancreatic cancer
A research group at the Italian Institute of Technology (IIT-Istituto Italiano di Tecnologia) has identified a candidate molecule that could improve current therapies against pancreatic cancer. The team designed the new molecule, ...
9 hours ago
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'Molecular glue' stabilizes protein that inhibits development of non-small cell lung cancer
Lung cancer is the second-most common cancer and the leading cause of cancer death in the United States. Over 80% of lung cancers are non-small cell lung cancers, in which tumor cells are larger and grow more slowly than ...
8 hours ago
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Ultrasensitive liquid biopsy affective in predicting and monitoring immunotherapy response, study shows
Published today in Clinical Cancer Research, findings from a study led by investigators at the Vall d'Hebron Institute of Oncology (VHIO), which forms part of the Vall d'Hebron Campus, underscore the efficacy of analyzing ...
2 hours ago
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Link between tumor metabolism and drug efficacy in cancer cells may help advance precision chemotherapy
Chemotherapy drugs that target cancer cells without damaging normal cells remain one of the key goals of precision medicine in cancer treatment. The challenge is designing drugs that do this effectively.
10 hours ago
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New risk score helps predict pancreatic cancer recurrence
Cedars-Sinai investigators, leading a multi-institutional team, have developed and validated a tool to predict which patients with pancreatic neuroendocrine tumors (PanNETs) need closer monitoring because their cancer is ...
12 hours ago
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Giving less chemotherapy can still cure lymphoma patients in their 80s, study says
People aged 80 and older with a common type of lymphoma can take a half-dose of chemotherapy and be cured or significantly extend their survivorship with fewer toxic side effects, a new study shows.
8 hours ago
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How to reduce risk of lymphedema after head and neck cancer
Lymphedema after head and neck cancer is considerably more common than previously assumed and can persist long after cancer treatment has finished. Researchers at Lund University in Sweden have discovered that patients with ...
4 hours ago
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Black patients diagnosed with aggressive leukemia experience worse outcomes
Compared with white patients, Black patients with an aggressive form of leukemia—called acute myeloid leukemia (AML)—were on average more than five years younger at diagnosis and more than 30% more likely to die of their ...
11 hours ago
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New technology reduces false positives in breast ultrasounds
New ultrasound technology developed at Johns Hopkins can distinguish fluid from solid breast masses with near perfect accuracy, an advance that could save patients, especially those with dense breast tissue, from unnecessary ...
15 hours ago
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Alcohol-linked DNA damage tied to cancer risk: Study reveals repair enzyme's role
Alcohol consumption leads to the formation of a toxic compound called acetaldehyde, which damages DNA. A research team from IOCB Prague has now described in detail how cells repair this damaged genetic information.
Dec 16, 2025
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Ultrasound paired with vibrating nanoparticles softens tumor tissue, improving drug delivery
Cancer is one of the leading causes of death in the U.S., second only to heart disease. But a new cancer treatment method from CU Boulder researchers uses sound waves to soften tumors and could be a potent tool against the ...
Dec 16, 2025
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Multiple myeloma develops differently in men and women, study reveals
Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have uncovered biological differences in how multiple myeloma develops and progresses in men and in women. The rare blood cancer occurs ...
Dec 16, 2025
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New understanding of T cell receptors may improve cancer immunotherapies
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack dangerous cells. Yet a full ...
Dec 16, 2025
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Colorectal cancer's immune puzzle cracked: Two Treg cell types shape survival odds
In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system's ability to fight against a tumor.
Dec 16, 2025
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Protein therapy boosts immune attack on tumors by reversing sugar 'brakes'
Researchers at MIT and Stanford University have developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make cancer immunotherapy work for many more patients.
Dec 16, 2025
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Blood test can detect single lung cancer calls using infrared technique
A UK research team has developed a pioneering blood test that could change the way lung cancer is detected and monitored.
Dec 16, 2025
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Custom 3D-printed models improve precision of oral cancer removal
Using 3D modeling to plan and guide cancer surgeries increases surgical precision, resulting in complete tumor removal for 92% of head and neck cancers that have invaded bone, according to a new study published by The Ohio ...
Dec 16, 2025
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Combination therapy shows potential to treat pediatric brain cancer ATRT
St. Jude Children's Research Hospital scientists have identified a promising combination approach to treat a rare but catastrophic pediatric brain cancer called atypical teratoid rhabdoid tumor (ATRT).
Dec 16, 2025
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Blood analysis shows whether brain cancer treatment is working
The effectiveness of chemotherapy for brain cancer, done with a technique that opens the blood-brain barrier, can be monitored by blood draw, researchers at Northwestern Medicine and the University of Michigan have shown.
Dec 16, 2025
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Medical patients face hidden time burdens: An overlooked cost of cancer care
Treatments for serious illnesses like cancer can be enormously time-consuming. Yet most research on cancer-related time burdens has relied on hospital administrative data and medical records—information that captures appointment ...
Dec 16, 2025
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Cancer messenger substances disrupt muscle function and trigger muscle breakdown
Cancer patients often lose excessive amounts of weight. This affects up to 80% of patients and is mainly due to a decrease in muscle mass and fatty tissue. This cancer-induced cachexia (CIC) is triggered by cancer cytokines, ...
Dec 16, 2025
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Lab platform models human organs to test cancer drug toxicity without animals
Overcoming acquired treatment resistance is one of the major challenges in the fight against cancer. While combination therapies hold promise, their toxicity to healthy tissue remains a major hurdle.
Dec 16, 2025
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Differences persist in cancer mortality burden by where patients live, socioeconomic status, race/ethnicity
In new research on the status of cancer disparities in the United States, American Cancer Society (ACS) scientists report higher cancer mortality rates among adults living in rural areas, certain congressional districts, ...
Dec 16, 2025
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