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Oncology & Cancer news

Oncology & Cancer

All in the blood: New way to detect drug resistance in ovarian cancer patients

Researchers from the Walter and Eliza Hall Institute (WEHI)in Australia have found a new way to predict a subset of patients who are likely to become resistant to PARP inhibitors (PARPi), a key therapy used to treat ovarian ...

Oncology & Cancer

Study shows mechanical stiffness of tissue can alter fate of tumor cell populations

Ongoing fundamental research on cancer cells could be used to create new drugs and therapies that fight the spread of cancer cells. The work of Dr. Tanmay Lele, joint faculty in chemical engineering, and chemical engineering ...

Oncology & Cancer

Detecting pancreatic cancer

November is National Pancreatic Cancer Awareness Month. Approximately 66,000 people in the U.S. will be diagnosed with pancreatic cancer this year, according to the National Cancer Institute.

Oncology & Cancer

'Moonlighting' enzymes may lead to new cancer therapies

Researchers at the Center for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating ...

Oncology & Cancer

Medicaid enrollment continuity tied to lymphoma stage at diagnosis

Continuous enrollment in Medicaid was associated with a lower rate of a late-stage lymphoma diagnosis in children and adolescents/young adults (AYAs). However, fewer than half of Medicaid-insured patients in these age ranges ...

Oncology & Cancer

How melanoma cells escape oxidative stress to metastasize

Investigators from Weill Cornell Medicine have discovered a defense mechanism that protects skin cancer cells from oxidative stress and helps them spread. The findings suggest a new drug target that could lead to therapies ...

Oncology & Cancer

Starving cancer cells of fat may improve cancer treatment

Cutting off cancer cells' access to fat may help a specific type of cancer treatment work more effectively, reports a study by Van Andel Institute scientists. The findings, published in Cell Chemical Biology, lay the groundwork ...

Oncology & Cancer

New CAR-T cells offer on-demand control for cancer treatment

Ludwig Cancer Research scientists have devised new types of chimeric antigen-receptor (CAR) T cells—a type of cancer immunotherapy—that can be switched on to varying degrees of intensity and then switched off on demand ...

Oncology & Cancer

Bioengineered antibodies target mutant HER2 proteins

For some proteins, a single mutation, or change in its DNA instructions, is all it takes to tip the balance between functioning normally and causing cancer. But despite causing major disease, these slightly mutated proteins ...