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Oncology & Cancer news
Oncology & Cancer
Trial finds quality of life similar among patients with low-risk DCIS whether they received active monitoring or surgery
Patients with low-risk ductal carcinoma in situ (DCIS) who underwent active monitoring reported comparable physical, emotional, and psychological outcomes to patients who received upfront treatment, according to results from ...
51 minutes ago
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Oncology & Cancer
Non-tumor cells in pancreatic cancer may reduce the effectiveness of the body's natural immune response
The relationship the immune system and stromal cells in pancreatic cancer can have a significant impact on patients' survival rates, according to findings of a Queen Mary-led study.
46 minutes ago
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Study finds chest wall irradiation may be unnecessary for many breast cancer patients
Patients with intermediate-risk breast cancer had similar rates of 10-year overall survival whether or not they underwent chest wall irradiation (CWI) after mastectomy, according to results from the BIG 2-04 MRC SUPREMO clinical ...
56 minutes ago
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COMET trial finds active monitoring is a viable option for some patients with low-risk DCIS
Among patients with hormone receptor (HR)-positive, HER2-negative, low-risk ductal carcinoma in situ (DCIS), those who underwent active monitoring had similar two-year invasive ipsilateral breast cancer recurrence rates as ...
54 minutes ago
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Clinical trial: Adjuvant tamoxifen may reduce recurrence risk for patients with 'good-risk' DCIS who forgo radiation
For patients with "good-risk" ductal carcinoma in situ (DCIS) who underwent breast-conserving surgery and did not receive radiotherapy, tamoxifen significantly decreased the risk of recurrence in the same breast, according ...
56 minutes ago
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Prostate cancer incidence, mortality rates mainly stable, decreasing
In most countries, prostate cancer incidence and mortality rates decreased or were stable in the most recent five-year period, but increasing trends were seen in some countries, according to a study published online Dec. ...
4 hours ago
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Machine learning reveals a functional network of genes and proteins in human cancer
Large-scale protein and gene profiling have massively expanded the landscape of cancer-associated proteins and gene mutations, but it has been difficult to discern whether they play an active role in the disease or are innocent ...
20 hours ago
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Tumors grow larger in female fruit flies than males. Here's what that could mean for humans
A study by Tulane University researchers has uncovered new insights into how biological sex differences can influence tumor growth. The findings, published in Science Advances, could lead to a better understanding of cancer ...
20 hours ago
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RNA fragment is key regulator of gene expression and potential therapeutic target in cancer, study reveals
A novel study from Korea uncovers the process of synthesis and pivotal role of the transfer RNA-derived fragment, 5′-tRH-GlyGCC, in cancer progression. By interacting with splicing factors, it regulates gene expression, ...
22 hours ago
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Organoids represent the complex cell landscape of pancreatic cancer
A team led by researchers at the Technical University of Munich (TUM) has, for the first time, grown tumor organoids—three-dimensional miniature tumors in the laboratory—that mimic the different structures and characteristics ...
23 hours ago
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DNA sequencing test can predict prognosis for advanced prostate cancer patients
Published in Nature Communications, a new study led by the University of Minnesota Medical School and Duke University found that a DNA sequencing test for advanced prostate cancer patients can distinguish between patients ...
17 hours ago
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Predictors for radiotherapy success may help some rectal cancer patients avoid surgery
Recent research from the S:CORT team has identified key biomarkers and treatment strategies that predict and enhance effectiveness of radiotherapy in rectal cancer treatment.
18 hours ago
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Next-generation treatment protects against progression in some patients with advanced breast cancer
Imlunestrant, an investigational next-generation selective estrogen receptor degrader (SERD), improved progression-free survival in patients with endocrine therapy-pretreated, ER-positive, HER2-negative advanced breast cancer—as ...
20 hours ago
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Comprehensive database documents sex differences in cancer biology
A new database could lead to vast improvements in precision oncology by documenting sex-based differences in cancer treatment efficacy, biomarkers, risk factors, and microbial influences across 71 cancer types. The database—created ...
20 hours ago
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Esophageal cancer: Global data reveal growing burden as BMI and tobacco use rise
Esophageal cancer remains a major health threat worldwide, with considerable regional disparities in incidence and mortality. Key modifiable risk factors—smoking, alcohol consumption, and obesity—are closely linked to ...
17 hours ago
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Advances in carbon ion therapy show promise for challenging large sacral tumors
A pioneering study has introduced a novel approach to enhance the treatment of large sacral chordomas using carbon ion therapy. The study focuses on optimizing dose-averaged linear energy transfer (LETd), a critical parameter ...
17 hours ago
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Intraarterial radionuclide therapy found safe and effective for advanced meningioma patients
Radionuclide therapy delivered directly to an artery is safe and feasible for patients with advanced meningioma, according to new research published in the December issue of The Journal of Nuclear Medicine. In the first long-term ...
18 hours ago
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Sardines, mackerel and other oily fish: The benefits of marine lipids in the fight against cancer
The world's oceans represent a vast and largely untapped source of biodiversity, offering a high probability for the discovery of unique chemical compounds with therapeutic properties. Among these, bioactive molecules found ...
20 hours ago
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King Charles is changing his diet to keep his cancer at bay—here's what the evidence says
King Charles's decision to cut red meat from his diet following his cancer treatment has sparked a frenzy of interest in the potential effect of what we eat on cancer outcomes, and how well people do after they're diagnosed.
22 hours ago
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Cancer therapy shows long-term survival benefits for patients with high-risk, BRCA-positive breast cancer in trial
Patients with high-risk, BRCA-positive breast cancer who received olaparib (Lynparza) after standard treatment continued to have better survival outcomes than those who received placebo after a median follow-up of 6.1 years, ...
22 hours ago
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New path toward faster drug approvals for multiple myeloma treatment
A new review published in Blood Cancer Discovery outlines a major multiple myeloma research project that supported a key regulatory decision by a U.S. Food and Drug Administration committee. The decision greenlights a new ...
22 hours ago
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Clinical practice guideline updated for radiation therapy for rectal cancer
In a clinical practice guideline issued by the American Society for Radiation Oncology and published online Nov. 25 in Practical Radiation Oncology, updated recommendations are presented for the use of radiation therapy (RT) ...
20 hours ago
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BRCA-mutation carriers with history of early-onset breast cancer may benefit from risk-reducing surgery
Patients with germline BRCA mutations who were diagnosed with breast cancer at or before age 40 and who underwent a bilateral risk-reducing mastectomy (RRM) and/or a risk-reducing salpingo-oophorectomy (RRSO) had lower rates ...
22 hours ago
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Oncologist talks personalized medicine for pancreatic cancer
Cancer researchers at Fox Chase Cancer Center in Philadelphia see promise in personalized medicine to help crack the code on improving diagnosis and treatment options for pancreatic cancer.
Dec 11, 2024
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How this cancer drug could make radiation a slam dunk therapy
Radiation is one of the most effective ways to kill a tumor. But these therapies are indiscriminate, and they can damage healthy tissues.
Dec 10, 2024
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