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Oncology news

New findings link obesity to loss of natural breast cancer protection

A research team at Huntsman Cancer Institute at the University of Utah (the U) has found that obesity prevents a biological process that kills cancerous cells, revealing a possible reason obesity is a risk factor for breast ...

New 'smart' nanoparticles help the immune system better attack tumors

Adelaide University researchers have developed a new way to use mRNA technology to reprogram tumor-supporting immune cells and strengthen the body's anticancer immune response.

Protein linked to cell death may also drive liver cancer

New research from the University of Oklahoma identifies a protein in liver cells that appears to help drive the development of liver cancer associated with obesity-related fatty liver disease. The finding, published in Hepatology, ...

Child cancer groups call for concerted action

It's one of the cruelest ironies in health and medicine. Pediatric sarcomas are among the rarest yet most aggressive forms of childhood cancer and some of the hardest to cure. Whereas many adult cancers are now treatable ...

Exploring precision medicine for pancreatic cancer

Imagine if, before starting cancer care, doctors could rapidly identify the most effective chemotherapy, immunotherapy or combination to personalize treatment for a loved one's hard-to-treat pancreatic cancer and improve ...

A unified framework to explain one of cancer's major drivers

In a rare pair of papers published back-to-back in the journal Genes & Development, research teams led by senior author Anindya Bagchi, Ph.D., associate professor in the Cancer Genome and Epigenetics Program at Sanford Burnham ...

How 'undead' cells trigger cancer-promoting inflammation

Stopping tumor growth is only half the battle. Rather than killing tumor cells, many cancer therapies can only push them into cellular senescence, a state in which cells stop dividing but do not die. These "undead" cells ...

How highly aggressive colon cancer evades the immune system

Researchers from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute have identified a previously unknown mechanism by which a particularly aggressive form of colon cancer evades the immune system.

Math and medicine join forces to solve a cancer mystery

Immunotherapy has transformed outcomes for many cancer patients. Unlike conventional treatments, these therapies do not attack tumors directly. Instead, they enable the body's immune system to identify and kill cancer cells ...