Cell therapy fights lethal childhood brain cancer in clinical trial
An immune-cell therapy shrank children's brain tumors, restored neurologic function and—for one participant in a Stanford Medicine clinical trial—erased all detectable traces of a brain cancer typically considered incurable.
11 hours ago
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In 10 seconds, an AI model can detect cancerous brain tumor often missed during surgery
Researchers have developed an AI-powered model that—in 10 seconds—can determine during surgery if any part of a cancerous brain tumor that could be removed remains, a study published in Nature suggests.
11 hours ago
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Scientists create an scRNA-seq atlas of the multiple myeloma immune microenvironment across disease stages
Multiple myeloma (MM) is an incurable blood cancer, leading to weakened immunity, bone damage, and other serious health issues. The high relapse rates following initial treatments make the search for novel immunotherapies ...
5 hours ago
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Genetic changes linked to testicular cancer offer fresh insights into the disease
Scientists have identified new gene faults and evolutionary patterns contributing to testicular cancer. Their findings offer profound insights into the development of the disease and into potential treatment strategies.
11 hours ago
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Treatment advances and predictive biomarkers stand to improve bladder cancer care
Recent advances in bladder cancer treatments may offer hope of curative care to more patients, including those with high-risk localized, muscle-invasive disease, according to an editorial published in the New England Journal ...
5 hours ago
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MRI-guided radiation therapy shown to reduce long-term side effects for patients with prostate cancer
After a comprehensive two-year follow-up, researchers at the UCLA Health Jonsson Comprehensive Cancer Center found that MRI-guided stereotactic body radiotherapy (SBRT) for prostate cancer significantly reduced long-term ...
7 hours ago
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Self-reported screening can reduce distressing symptoms for pediatric patients with cancer
Regular, self-reported symptom screening was associated with reduced symptom burden when compared with usual care for pediatric patients with cancer, according to new research led by scientists at the University of Toronto ...
5 hours ago
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Detecting pancreatic cancer
November is National Pancreatic Cancer Awareness Month. Approximately 66,000 people in the U.S. will be diagnosed with pancreatic cancer this year, according to the National Cancer Institute.
11 hours ago
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Clinical trial shows immunotherapy drug pembrolizumab improves outcomes for patients with soft tissue sarcoma
Addition of the immunotherapy drug pembrolizumab to standard of care for patients with advanced soft tissue sarcoma of the limb significantly improved disease-free survival, according to the results of the SU2C-SARC032 clinical ...
Nov 12, 2024
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New study links air pollution with higher rates of head and neck cancer
A recent study published in the journal Scientific Reports correlates higher levels of pollutant particulate matter to higher occurrences of head and neck aerodigestive cancer.
Nov 12, 2024
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Glioblastoma: New treatment uses CAR-T cells to attack brain tumors from multiple angles
Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this aggressive tumor permanently disappear. The tumor cells are too varied, and the microenvironment is ...
Nov 12, 2024
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New cancer therapy strategy targets GLUT3 in regulatory T cells to supercharge anti-tumor immunity
Scientists at Pohang University of Science and Technology (POSTECH) and ShanghaiTech University have achieved a breakthrough in cancer immunotherapy research. Led by Professors Sin-Hyeog Im and Dipayan Rudra, the research ...
Nov 12, 2024
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Combination approach shows promise for treating rare, aggressive cancers
A research team led by UCLA Health Jonsson Comprehensive Cancer Center investigators has shown that combining pembrolizumab, an immunotherapy drug, with standard chemotherapy can improve treatment outcomes for patients with ...
Nov 12, 2024
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'Moonlighting' enzymes may lead to new cancer therapies
Researchers at the Center for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within the nucleus, orchestrating ...
Nov 12, 2024
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Researchers discover why taking a mushroom supplement slows or prevents prostate cancer from getting worse
Researchers at City of Hope now understand why taking an investigational white button mushroom supplement shows promise in slowing and even preventing prostate cancer from spreading among men who joined a phase 2 clinical ...
Nov 12, 2024
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Only half of young cancer patients report a discussion on fertility preservation, researchers find
Only half of people with early-onset cancers reported discussing fertility preservation options prior to their oncology treatments, according to results of a cross-sectional study published Nov. 12 in JAMA Network Open.
Nov 12, 2024
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Study finds 81% of cancer cures touted by TikTok videos are fake
As many as 81% of cancer cures touted by content creators on TikTok are fake, according to new research from City St George's, University of London.
Nov 12, 2024
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AI tools measure 'immunological fitness' to personalize cancer therapies
Researchers from the Data Science and Artificial Intelligence Institute (DATAI) at the University of Navarra have developed artificial intelligence (AI) models to personalize immune therapies for oncology patients.
Nov 12, 2024
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Inhibiting METTL3 protein shows promise for high-risk neuroblastoma
Blocking the METTL3 protein can increase sensitivity to chemotherapy in neuroblastoma, according to research from the University of Gothenburg. The study shows how specific RNA modifications affect gene expression in the ...
Nov 12, 2024
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Study identifies new approach to overcome docetaxel resistance in patients with advanced prostate cancer
The treatment landscape for patients with prostate cancer, especially individuals with advanced disease, has dramatically changed in recent years. However, aside from drug or hormonal therapies, other targets to treat prostate ...
Nov 12, 2024
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New blood test offers early detection of drug-induced tissue damage in cancer patients
A team of researchers have applied a novel blood test that can detect early signs of potentially fatal lung damage in cancer patients taking antibody–drug conjugates (ADCs). This breakthrough method aims to offer a safer, ...
Nov 12, 2024
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Treatment target for aggressive leukemia discovered by disrupting its genome organization
Researchers have identified a key weakness in acute myeloid leukemia, offering a promising new strategy to delay the progression of this aggressive blood cancer. The discovery focuses on disrupting the function of a certain ...
Nov 12, 2024
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Medicaid enrollment continuity tied to lymphoma stage at diagnosis
Continuous enrollment in Medicaid was associated with a lower rate of a late-stage lymphoma diagnosis in children and adolescents/young adults (AYAs). However, fewer than half of Medicaid-insured patients in these age ranges ...
Nov 12, 2024
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