Researchers from the Organoid group at the Hubrecht Institute have found that specific gut cells, BEST4/CA7+ cells, regulate electrolyte and water balance in response to bacterial toxins that cause diarrhea. Their findings, ...
Feb 25, 2025
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An inhalable medicine with the potential to improve lung disease in people with cystic fibrosis, irrespective of their mutation type, is being tested in human trials in the UK and Europe.
Feb 20, 2025
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Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers from the Technical University of Munich (TUM) have discovered that the disease causes changes in ...
Feb 6, 2025
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Gene-editing therapies—techniques that modify DNA to treat or prevent disease—have the potential to transform the field of drug development. By making precise edits to the genome, problematic genes could be modified or eliminated, ...
Oct 21, 2024
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Cystic fibrosis is one of the most common genetic disorders, causing thick mucus build-up in the lungs and other parts of the body, breathing problems, and infection. A three-drug cocktail known as Trikafta has greatly improved ...
Jul 10, 2024
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A team of University of Saskatchewan (USask) researchers are exploring the role of a newly identified cell type in cystic fibrosis (CF), which could lead to effective new types of treatment.
Apr 29, 2024
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University of Queensland researchers have identified an opportunity to reduce infections in people living with cystic fibrosis (CF). Professor Matt Sweet, Dr. Kaustav Das Gupta and Dr. James Curson from UQ's Institute for ...
Feb 23, 2024
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A new study by University of Iowa researchers finds that rare lung cells known as pulmonary ionocytes facilitate the absorption of water and salt from the airway surface. This function is exactly the opposite of what was ...
Oct 23, 2023
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Two nationally recognized experts in cloning and stem cell science from the University of Houston, Wa Xian and Frank McKeon, are reporting that five lung stem cell variants dominate the lungs of patients with advanced cystic ...
Sep 27, 2023
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Influenza infection (flu) is a major cause of death around the world, especially during years of flu pandemics. People who die of the flu often have a secondary lung infection with Staphylococcus aureus (staph) bacteria that ...
Aug 15, 2023
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