There's still much to learn about how doxorubicin, a 50-year-old chemotherapy drug, causes its most concerning side effects. While responsible for saving many lives, this treatment sometimes causes cardiac damage that stiffens ...
Jul 17, 2024
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T cells—the body's foot soldiers against invaders, ranging from everyday infections to cancers—are integral to many successful immunotherapies. However, a frustrating factor is that immunotherapies do not always work.
May 6, 2024
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Glaucoma is one of the leading causes of blindness worldwide, and vision loss, due to the loss of retinal ganglion cells (RGCs), cannot currently be reversed with any treatment. Some studies have looked at replacing RGCs ...
Nov 18, 2023
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When fighting disease, our immune cells need to reach their target quickly. Researchers at the Institute of Science and Technology Austria (ISTA) have now discovered that immune cells actively generate their own guidance ...
Sep 1, 2023
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Cardiovascular diseases, particularly acute myocardial infarction, are the leading cause of disability and death. Atherosclerosis, the pathological basis of AMI, can be accelerated by chronic inflammation. Ulcerative colitis ...
Jun 15, 2023
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Sometimes in the laboratory there are unexpected results. "Previously it had been observed that autoantibodies are common in severe COVID patients, those who end up in intensive care," says Jonathan Muri, postdoctoral fellow ...
Mar 6, 2023
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Some people and animals grow arteries that allow blood to bypass blockages in the heart. But to engineer these bypasses to serve as lifelines, scientists first need to understand how they work. Researchers have now modeled ...
Aug 29, 2022
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Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers ...
Jul 15, 2022
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