Combination therapy is essentially a one-two punch at cancer—sometimes with multiple punches. For people with lung cancer, it means treating a tumor with more than one type of therapy at the same time or in sequence, often ...
Mar 30, 2026
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Drugs that block enzymes called tyrosine kinases are among the most effective targeted therapies for cancer. However, they typically work for only 40% to 80% of the patients who would be expected to respond to them. In a ...
Mar 26, 2026
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Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 inhibition offers an indirect ...
Mar 13, 2026
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Asthma affects millions of people worldwide, and adult women experience the condition more frequently—and often more severely—than men. Symptoms can also fluctuate during puberty, pregnancy and menopause, yet the biological ...
Feb 11, 2026
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A paper published in Biology Methods and Protocols, indicates that a new computational method may help researchers identify effective precision treatments for cancer more quickly and efficiently. The paper is titled "SOLVE: ...
Jan 28, 2026
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Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified why certain lung cancer cells become highly resistant to treatment after developing mutations in a key gene called EGFR (epidermal ...
Jan 25, 2026
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In Brazil, the early detection of genetic alterations in lung cancer through liquid biopsies could be a valuable tool for expediting diagnoses and guiding patient treatment.
Jan 7, 2026
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Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too often they don't make it that far. A new study shows how this Trojan Horse strategy works better by exploiting ...
Nov 25, 2025
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A study led by University of Cincinnati Cancer Center researchers sheds new light on how pancreatic cancer cells resist treatment and points to potential new combination therapies to make treatments more effective.
Nov 24, 2025
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One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, according to a new study published November 5, 2025, in npj Precision Oncology.
Nov 14, 2025
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