Yale School of Medicine (YSM) researchers have made key breakthroughs in understanding how to treat fibrotic diseases such as scleroderma and graft-versus-host disease.
Nov 14, 2025
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Alzheimer's disease (AD) is a neurodegenerative condition that typically affects older people and is the leading cause of dementia worldwide. AD is characterized by progressive cognitive impairment caused by a decades-long ...
Sep 16, 2025
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An international team of scientists has revealed how rogue rings of DNA that float outside of our chromosomes—known as extrachromosomal DNA, or ecDNA—can drive the growth of a large proportion of glioblastomas, the most common ...
Sep 8, 2025
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A study published in PNAS has found that for people with a rare form of ichthyosis, medications previously used to treat cancer could be repurposed for treatment.
Aug 26, 2025
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Using mathematical analysis of patterns of human and animal cell behavior, scientists say they have developed a computer program that mimics the behavior of such cells in any part of the body. Led by investigators at Indiana ...
Jul 25, 2025
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Radiation therapy can promote the epidermal growth factor receptor (EGFR) ligand amphiregulin, which increases growth of existing metastases in patients with advanced solid tumors, according to a study recently published ...
Jul 12, 2025
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Increased activity in a specific biological pathway may explain why many patients with a deadly form of skin cancer do not respond to the latest cancer treatments, a new study shows.
Jun 10, 2025
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A dual-target CAR T cell therapy approach shows promise for slowing tumor growth in a notoriously aggressive and fast-growing brain cancer. Tumors became smaller after the experimental CAR T cell therapy in nearly two-thirds ...
Jun 1, 2025
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Treatment resistance and relapse in the most common type of lung cancer can be traced to a protein called agrin, according to a preclinical study led by Roswell Park Comprehensive Cancer Center. Results of the study, led ...
Apr 11, 2025
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In a recent study, precancerous pancreatic lesions and some pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations had higher-than-normal expression of the FGFR2 protein, and FGFR2 inactivation delayed KRAS-mutated ...
Apr 2, 2025
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