Studying mismatches between donor and recipient in kidney transplantation
A recent study found new ways to identify mismatches between donors and recipients in kidney transplantation.
Oct 6, 2023
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Amino Acid, Peptide, or Protein: HLA Antigens
Medical news and research articles
Study: The human body may possess a secret weapon against SARS-CoV-2
An obscure class of molecules, part of the vast system that helps the human body distinguish "self" from "non-self," may also hold the key to stopping SARS-CoV-2 from commandeering healthy cells, scientists have found in ...
Gene mutation may explain why some don't get sick from COVID-19
People who contract COVID-19 but never develop symptoms—the so-called super dodgers—may have a genetic ace up their sleeve. They're more than twice as likely as those who become symptomatic to carry a specific gene variation ...
Jul 19, 2023
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New tool predicts if immunotherapy will mistakenly attack healthy cells
Researchers at the University of Houston are working to make T-cell immunotherapy safer, developing a tool called CrossDome, which uses a combination of genetic and biochemical information to predict if T-cell immunotherapies ...
Jun 14, 2023
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Team discovers near-universal T cell immunity towards a broad range of bacteria
Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. As reported in the journal Immunity, an international team of scientists have discovered ...
Apr 25, 2023
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Creating a versatile vaccine to take on COVID-19 in its many guises
One of the 12 labors of Hercules, according to ancient lore, was to destroy a nine-headed monster called the Hydra. The challenge was that when Hercules used his sword to chop off one of the monster's heads, two would grow ...
Mar 10, 2023
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Researchers identify molecules that optimize immune presentation of antigens across the human population
Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, a finding that could ...
Feb 24, 2023
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Collaborative initiative to unravel the role of HLA in individuals with a genetic cancer predisposition
Scientists from the Heidelberg Institute for Theoretical Studies (HITS), the German Cancer Research Center (DKFZ), the Heidelberg University Hospital and Heidelberg University have established INDICATE, an international collaborative ...
Oct 21, 2022
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Researchers test a novel hypothesis to explain the cause of autoimmunity in patients with type 1 diabetes
Type 1 diabetes (T1D) is an autoimmune disease in which the pancreas makes little or no insulin. The details on the events that occur during autoimmune destruction of the pancreatic beta-cells have been studied extensively ...
Sep 23, 2022
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Hepatitis cases in children linked to adeno-associated virus AAV2
Recent acute hepatitis cases of unknown origin in children have now been linked to the virus AAV2 in two new U.K. studies, with no evidence of a direct link to SARS-CoV-2 infection.
Jul 25, 2022
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