Drug targets with human genetic evidence are more likely than those without to be clinically translatable and thus enter phase II/III clinical trials or be approved for marketing more quickly, which will likely significantly ...
Mar 26, 2024
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Researchers have studied the association of proprotein convertase subtilisin/kexin type 9 (PCSK9) with soluble P-selectin (sP-selectin) and their values in predicting major adverse cardiovascular events (MACE) at one-year ...
Jan 8, 2024
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27
Nearly two in five U.S. adults have high cholesterol, according to the Centers for Disease Control and Prevention (CDC). Untreated, high cholesterol can lead to heart disease and stroke, which are two of the top causes of ...
Dec 18, 2023
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Prescription drugs and vaccines revolutionized health care, dramatically decreasing death from disease and improving quality of life across the globe. But how do researchers, universities and hospitals, and the pharmaceutical ...
Dec 14, 2023
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A recent trial of a novel gene-editing technique that lowered dangerously high cholesterol by up to 55% has generated talk of a new front opening against cardiovascular disease, which kills nearly 700,000 Americans each year ...
Dec 13, 2023
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Two new gene-editing treatments that target dangerously high levels of cholesterol in people with a genetic predisposition to the condition were found safe and effective in new, groundbreaking research.
Nov 18, 2023
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A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very ...
Nov 13, 2023
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Chronic kidney disease is a growing problem both in Denmark and internationally. Now, a new study from Aarhus University reveals that a protein known for treating cardiovascular diseases also counteracts a mechanism in the ...
Jul 10, 2023
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In a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has succeeded in a world first: they've found the molecular mechanism by which the ...
Jan 19, 2023
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Why are certain body parts more prone to skin diseases than others?
Sep 23, 2022
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