Researchers at the Icahn School of Medicine at Mount Sinai have identified a previously hidden druggable site in a cancer-related protein that could open the door toward the development of a new generation of more precise ...
Jun 3, 2026
0
7
The U.S. Food and Drug Administration (FDA) has approved vimseltinib (Romvimza) for adult patients with a rare condition called tenosynovial giant cell tumor (TGCT). TGCT is a tumor of the tissue that lines the joints.
Feb 20, 2025
0
18
Preclinical research findings from the University of North Carolina Lineberger Comprehensive Cancer Center have identified a cocktail of three different drugs that can be used to generate more robust immune system CAR-Ts ...
Jan 13, 2025
0
29
Treatment with BAY 2927088 led to rapid, substantial, and durable responses in patients with heavily pretreated HER2-mutant non-small cell lung cancer (NSCLC), according to research presented at the International Association ...
Sep 9, 2024
0
24
As an extremely aggressive form of skin cancer, cutaneous melanoma, is still associated with a high mortality rate. Enormous progress has recently been made in the fight against deadly metastasis, but existing therapeutic ...
Nov 21, 2023
0
58
For certain patients with advanced breast cancer, a drug called Piqray (alpelisib) may extend survival. But new research confirms the medication often causes seriously high blood sugar levels.
Sep 25, 2023
0
76
New research in the June 2023 issue of Journal of the National Comprehensive Cancer Network has found that when alectinib—a safe and effective small molecule kinase inhibitor used to treat some types of advanced lung cancer—was ...
Jun 12, 2023
0
56
A new editorial paper titled "Unlocking the potential of molecular-driven stratification for osteosarcoma treatment and prognosis" has been published in Oncotarget.
Mar 20, 2023
0
30
More than 70 FDA-approved cancer drugs are kinase inhibitors, which work by blocking kinases—enzymes that add phosphate groups to molecules in the cell—and preventing the chemical activity necessary for signaling and growth ...
Feb 13, 2023
0
67
Early trials of the targeted drug repotrectinib suggest that it could help treat patients with a certain type of non-small cell lung cancer (NSCLC).
Oct 28, 2022
0
78
