Cancer cells have the capacity to multiply rapidly. The aggressive cancer cells undergo conversion from their tightly connected epithelial state into a mesenchymal state, which lacks contact restrictions and spreads easily ...
Jul 2, 2025
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Ovarian cancer remains the leading cause of death among cancers affecting the female reproductive system, largely because current treatments are not effective once the cancer has spread (metastasized) beyond the ovaries.
May 13, 2025
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Colorectal cancer is the second leading cause of cancer-related death globally. Although some of the molecular changes associated with colorectal cancer are known, how they contribute to cancer development is not yet well ...
May 13, 2025
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Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide, with more than one million new diagnoses annually. Unfortunately, many cases are detected at advanced stages due to the lack of clear early symptoms, ...
Apr 1, 2025
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Researchers at Karolinska Institutet, led by Dr. Helin Norberg and Dr. Erik Norberg, have identified a previously unknown mechanism that affects the ability of cancer cells to spread in the body. The study, published in EMBO ...
Mar 10, 2025
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A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers, along with a new druggable therapeutic target to block it. The findings, published ...
Jan 28, 2025
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An international team of researchers has identified a key genetic mechanism that regulates the formation and migration of cranial neural crest cells, which are essential for developing facial structures.
Dec 13, 2024
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Neuroblastoma (NB), the most prevalent extracranial solid tumor in children, poses a significant therapeutic challenge due to its metastasis and high heterogeneity. A recent study leveraging single-cell RNA sequencing (scRNA-seq) ...
Nov 4, 2024
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Understanding in depth how tumors evolve to become malignant is the objective of a study recently published in the journal Nature Cancer. The findings demonstrate that within each tumor, groups of cells receive instructions ...
Oct 16, 2024
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A powerful new analytical tool offers a closer look at how tumor cells "shape-shift" to become more aggressive and untreatable, as shown in a study by researchers at Weill Cornell Medicine and the New York Genome Center.
Sep 24, 2024
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