Cell Function: type I interferon-mediated signaling pathway

Medical news and research articles

How a mitochondrial mutation rewires immune function

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single ...

SMYD3 enzyme found to suppress antiviral immune response

Interferon regulatory factor 3 (IRF3) is a key transcription factor in the type I interferon signaling. Its activation must be tightly controlled to efficiently activate innate immunity while avoiding its overactivation. ...

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