A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew themselves. Decades of research have shown that disruption of this pathway is a defining feature of many ...
5 hours ago
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A study led by José A. Seoane, Head of the Vall d'Hebron Institute of Oncology's (VHIO) Computational Biology Group identifies for the first time the exposome footprint—the set of environmental and lifestyle exposures—in ...
Apr 21, 2026
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Researchers at Åbo Akademi University have identified a new molecular change in patients with colorectal cancer and developed a genetic disease model that forms tumors in the large intestine, resembling those seen in patients. ...
Feb 10, 2026
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The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, new research reveals.
Dec 5, 2025
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Colorectal cancer is the second leading cause of cancer-related death globally. Although some of the molecular changes associated with colorectal cancer are known, how they contribute to cancer development is not yet well ...
May 13, 2025
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Alarming trends show that colon—or bowel—cancer is increasing in younger people. If the rise continues, colorectal cancer is projected to become the leading cause of cancer-related deaths among young adults globally by 2030.
Apr 29, 2025
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A gene called high mobility group A1 (HMGA1) may be the key that opens the door to the development of colon cancer, according to research led by investigators from the Johns Hopkins Kimmel Cancer Center, Johns Hopkins Department ...
Feb 20, 2025
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The genetic confirmation of a suspected diagnosis of hereditary colorectal cancer is of great importance for the medical care of affected families. However, many of the variants identified in the known genes cannot yet be ...
Oct 1, 2024
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Cancer, as a life-threatening disease, has been a major research focus. Understanding the mechanisms of tumor progression has been a significant challenge. In recent years, increasing evidence has indicated a correlation ...
Jan 9, 2024
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Genetic confirmation of the suspected diagnosis of "hereditary colorectal cancer" is of great importance for the medical care of affected families. However, many of the variants identified in the known genes cannot currently ...
Dec 7, 2023
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