A research team led by Prof. Patrizia Agostinis (VIB-KU Leuven) has found that melanoma cell populations protect themselves from a form of cell death called ferroptosis by secreting the lipoprotein apolipoprotein E (ApoE). ...
Oct 17, 2024
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A research team comprising several researchers within the University of Kentucky's Sanders-Brown Center on Aging has investigated the genetic risk of neuropathological traits commonly seen by neuropathologists performing ...
Oct 9, 2024
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In a study recently published in Alzheimer's & Dementia, researchers at Karolinska Institutet and Shandong Provincial University have reported the polygenic risk scores (PRS) with and without apolipoprotein E (APOE) gene ...
Aug 30, 2024
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A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led ...
Jul 2, 2024
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For the neurons in the brain to work smoothly and be able to process information, the central nervous system needs a strictly regulated environment. This is maintained by the blood–brain barrier, whereby specialized brain ...
Mar 22, 2024
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Identifying genetic variants and the role they play in predisposing people to Alzheimer's disease can help researchers better understand how to treat the neurodegenerative condition for which there is currently no cure.
Mar 21, 2024
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A new research paper titled "Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C" has been published in Aging.
Mar 13, 2024
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Alzheimer's disease (AD) is a debilitating incurable disease that affects millions of patients worldwide. Deposits of amyloid beta (Aβ) amyloid in the brain is key to AD pathology at early stages. Apolipoprotein E (apoE) ...
Dec 7, 2023
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Researchers at the University of Pittsburgh analyzed thousands of human genomes to find new gene variations responsible for controlling the levels of blood plasma molecules linked to Alzheimer's disease risk. The findings, ...
Sep 6, 2023
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Using data from diverse populations around the world, researchers from Children's Hospital of Philadelphia (CHOP) have developed an algorithm to help predict the risk of developing Alzheimer's disease based on genetic information ...
Jul 20, 2023
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