Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease in which the body's own immune system overreacts to minimal or inappropriate stimuli, producing recurrent attacks of fever and painful inflammation. ...
12 hours ago
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The dedicator of cytokinesis 10 (DOCK10) gene has been identified as a key driver of abnormal insulin secretion in insulinomas, as reported by researchers from Institute of Science Tokyo. Using surgical specimens and patient-derived ...
Mar 26, 2026
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By analyzing tissue from patients with Parkinson's disease, and animal and cellular models of the disease, a research team from the Institut de Neurociències of the UAB has shown that the main immune cells of the brain become ...
Feb 2, 2026
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A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and proposed that suppression ...
Aug 7, 2025
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Scientists at deCODE genetics, a subsidiary of AMGEN, have discovered rare sequence variants, predicted to cause a loss of function of ITSN1, that are associated with a high risk of Parkinson's disease. The findings also ...
Aug 15, 2024
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A new research paper titled "Roles of USP1 in Ewing sarcoma" has been published in Genes & Cancer.
Feb 14, 2024
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Superantigens are molecules that can stimulate a strong immune response by activating a large number of cytotoxic T cells, which are white blood cells that can eliminate tumor cells. One example of a superantigen is staphylococcal ...
Aug 14, 2023
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A new research paper was published in Oncotarget, titled, "Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines."
Mar 28, 2023
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A new research paper was published in Genes & Cancer on December 14, 2022, entitled, "Slit2 signaling stimulates Ewing sarcoma growth."
Jan 16, 2023
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