Safety and efficacy data from a phase 1 multicenter study evaluating rapcabtagene autoleucel, an investigational next-generation CD19-directed CAR-T cell therapy that is manufactured in 48 hours using the T-Charge platform, ...
Dec 9, 2025
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Nearly a third of families with children receiving chemotherapy for acute lymphoblastic leukemia (ALL)—the most common pediatric cancer—develop serious financial difficulties during their child's treatment, including ...
Dec 8, 2025
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A new type of cancer cell that "warrants urgent investigation" has been discovered in childhood leukemia and could impact clinical care. Research into new or repurposed treatments that target this new cell type could give ...
Nov 12, 2025
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Disrupted sleep is a common, often overlooked problem for pediatric patients being treated for acute lymphoblastic leukemia (ALL). To address this issue, researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders ...
Oct 27, 2025
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Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying RNA to stay one step ahead. Now, researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified ...
Sep 26, 2025
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Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might affect cancer growth.
Sep 11, 2025
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An international team led by the Clínic-IDIBAPS-UB along with the Institute of Cancer Research, London, has developed a new method based on DNA methylation to decipher the origin and evolution of cancer, which makes it possible ...
Sep 10, 2025
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Public concern continues to grow about the harmful effects of pesticides and other environmental pollutants, especially for children. Pesticides have previously been linked to a higher risk of developing childhood leukemia. ...
Sep 10, 2025
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Scientists at the University of Oxford, together with colleagues at Imperial College London and the University of Glasgow, have developed a new type of immunotherapy that could improve outcomes for infants and children with ...
Sep 3, 2025
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Children with acute lymphoblastic leukemia (ALL) from the lowest socioeconomic status (SES) neighborhoods have an increased risk for mortality, according to a study published online Aug. 22 in Blood Advances.
Aug 28, 2025
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