A novel, fixed-duration drug combination—consisting of a second-generation BTK inhibitor, called acalabrutinib, plus a BCL-2 inhibitor (venetoclax), with or without a third blood cancer drug—shows deep and durable responses ...
Dec 9, 2024
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Patients with relapsed or refractory CD19-positive B-cell acute lymphoblastic leukemia (ALL) who were treated with the novel anti-CD19 chimeric antigen receptor (CAR) T cell therapy, obecabtagene autoleucel (obe-cel), experienced ...
Nov 28, 2024
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The first time Becky Yu saw the Philadelphia skyline lit up at night was the evening she and her husband, Brian Currie, drove from their home in Delaware to Penn Medicine to begin her treatment for acute lymphocytic leukemia ...
Aug 8, 2024
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A significant survival improvement finding for adults with newly diagnosed BCR::ABL1-negative B-cell precursor acute lymphoblastic leukemia appears in the New England Journal of Medicine. The practice-changing finding is ...
Jul 24, 2024
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In clinical practice, traditional tumor-node-metastasis (TNM) staging has difficulty achieving accuracy in prognosis stratification at the individual patient level. In a study published in the journal Science Bulletin, researchers ...
Jul 5, 2024
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A new type of blood test can predict the recurrence of breast cancer in high-risk patients, months or even years before they relapse, research has shown.
Jun 3, 2024
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A U.S. Food and Drug Administration committee voted unanimously in April to approve a new clinical endpoint, minimal residual disease (MRD), when evaluating proposed drugs to treat multiple myeloma.
May 22, 2024
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Children with acute lymphoblastic leukemia (ALL) who live in extreme poverty and were undergoing maintenance therapy faced an almost two-fold greater risk of relapse compared with kids who weren't as poor, according to a ...
Apr 18, 2023
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Scientists at St. Jude Children's Research Hospital are reporting the most comprehensive study to date describing the variations in drug response across different genetic subtypes of acute lymphoblastic leukemia (ALL). The ...
Jan 5, 2023
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Patients with early-stage breast cancer who had a pathologic complete response (pCR) to neoadjuvant chemotherapy may be able to skip surgery and receive standard radiation treatment with a low chance of disease recurrence, ...
Oct 25, 2022
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