Researchers have uncovered that some childhood cancers have a substantially higher number of DNA changes than previously thought, changing the way we view children's tumors and possibly opening up new or repurposed treatment ...
May 29, 2025
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A research team at the University of Würzburg has gained new insights into the development of kidney tumors in young children. These enable a better risk assessment and could form the basis for targeted screening and improved ...
May 27, 2025
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A study led by the Joe C. Wen School of Population & Public Health at the University of California, Irvine has revealed possible links between exposure to per- and polyfluoroalkyl substances in drinking water and an increased ...
Feb 26, 2025
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Genetically tailored treatment plans for children with a type of kidney cancer could help provide the most effective care while minimizing side effects as much as possible.
Jan 23, 2025
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Hereditary changes in genes are often the cause of rare diseases. For example, disease-causing gene variants (PVs) in the HRAS gene cause Costello syndrome and PVs in the KRAS gene cause Noonan syndrome and cardio-facio-cutaneous ...
Sep 26, 2024
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Scientists at Van Andel Institute and Icahn School of Medicine at Mount Sinai have developed a potent anti-cancer compound that inhibits cancer cell growth in a tough-to-treat type of infant leukemia. The findings are published ...
Aug 30, 2024
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While kidney cancer is rare in children, Wilms tumor is the most common type found in kids, with between 500 and 600 children diagnosed annually in the U.S. The disease most often affects kids ages 3 to 4.
Apr 8, 2024
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An international team, led by researchers at Nagoya University in Japan, may have determined why the diffuse anaplasia (DA) subtype of Wilms tumor (WT) resists chemotherapy. This subtype grows even when it has a high burden ...
Feb 2, 2024
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A longstanding approach to surgeries for children with kidney tumors has been an abundance of caution.
May 1, 2023
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While Wilms tumor—also known as nephroblastoma—is rare, it is the most prevalent childhood kidney cancer. Researchers at Children's Hospital Los Angeles have now pinpointed a disruption in early kidney progenitor cell ...
May 1, 2023
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