A kidney drug may help restore fertility in premature ovarian insufficiency
A common kidney medication could be the key to treating a type of infertility that affects up to 3% of women under 40, according to a study published in Science.
Organic Chemical: finerenone
Medical news and research articles
Finerenone shows superior survival and kidney protection over spironolactone in diabetic kidney disease
Researchers from National Taiwan University Hospital and collaborating institutions have demonstrated that finerenone, a new-generation nonsteroidal mineralocorticoid receptor antagonist (MRA), significantly reduces the risk ...
Nov 26, 2025
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Finerenone reduces kidney damage in type 1 diabetes by lowering protein in urine
The drug finerenone has a positive effect on patients with type 1 diabetes and chronic kidney disease. The drug reduces the amount of proteins excreted in the urine of these patients. This reduction indicates that the degree ...
Nov 6, 2025
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Experts recommend SGLT-2 and GLP-1 only for adults at moderate to high risk of heart and kidney problems
SGLT-2 inhibitor and GLP-1 receptor agonist drugs should be used in all or almost all adults with type 2 diabetes at higher risk of cardiovascular and kidney complications, and in the majority of adults at moderate risk of ...
Aug 14, 2025
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FDA approves Kerendia for heart failure with ejection fraction of 40% or higher
Following priority review, the U.S. Food and Drug Administration approved Bayer's Kerendia (finerenone) for the treatment of patients with heart failure with left ventricular ejection fraction (LVEF) ≥40%.
Jul 15, 2025
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Combination therapy shows superior efficacy in reducing albumin in chronic kidney disease and type 2 diabetes patients
New data from the CONFIDENCE trial demonstrates that combination therapy with finerenone and empagliflozin leads to significantly greater reductions in albuminuria than either agent alone in patients with chronic kidney disease ...
Jun 5, 2025
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Event-free survival extended with long-term finerenone in heart failure
Long-term treatment with finerenone is estimated to extend event-free survival among people with heart failure with mildly reduced or preserved ejection fraction, according to a brief report published online Sept. 27 in JAMA ...
Sep 30, 2024
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Clinical trial finds finerenone reduces worsening heart failure and cardiovascular death
Finerenone reduced the composite of total first and recurrent heart failure (HF) events (hospitalizations for HF or urgent HF visits) and cardiovascular death in patients with HF and mildly reduced or preserved ejection fraction, ...
Sep 2, 2024
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Albuminuria reduction accounts for much of finerenone effect on CKD
For patients with chronic kidney disease (CKD) and type 2 diabetes, early albuminuria reduction accounts for a large proportion of the treatment effect of finerenone against CKD progression, according to a study published ...
Dec 5, 2023
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Focused update of heart failure guidelines published
A focused update of the European Society of Cardiology (ESC) Heart Failure Guidelines is published online today in European Heart Journal following the results of major new trials that should change the management of patients ...
Aug 25, 2023
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