Fentanyl and related variants of the synthetic opioid kill more Americans each year than car accidents and gun violence combined. In too-high doses, the drugs hijack brain chemistry and shut down the signals that control ...
Jun 12, 2026
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A new study exposes challenges in reversing opioid overdoses with naloxone when potent synthetic drugs like fentanyl and sufentanil are involved, according to a study published in the May 2026 issue of Anesthesiology. The ...
Apr 13, 2026
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Poisoning deaths from "novel" benzodiazepines (NBZDs)—designed to mimic brand-name drugs like Valium and Xanax but with greater potency—have spiked in the last six years. Out of nearly 260 fatal NBZD-related toxicity cases ...
Mar 10, 2026
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GHB-related deaths have increased 10-fold since 2013, while the number of hospitalizations more than tripled, according to an Australian-first study from the National Drug and Alcohol Research Center (NDARC) at UNSW Sydney. ...
Feb 3, 2026
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Researchers at USF Health are making dramatic strides in understanding how new opioid compounds work inside the body to provide pain relief, offering greater hope that new classes of these drugs may eventually be used to ...
Dec 18, 2025
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While the grip of the opioid epidemic is loosening, thanks in part to extensive public health efforts and rescue medications like Narcan, deaths from accidental overdose still threaten those who use synthetic opioids like ...
Aug 29, 2025
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University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional pain medications.
Apr 8, 2025
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The U.S. Food and Drug Administration has approved Spravato (esketamine) CIII nasal spray for adults living with major depressive disorder who have had an inadequate response to at least two oral antidepressants, according ...
Jan 22, 2025
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As the fentanyl crisis ravages communities across the country, toddlers and infants increasingly are becoming unsuspecting victims of an opioid that is 50 times more potent than heroin. Adults make up the vast number of fentanyl-related ...
Jul 19, 2024
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Opioids have long been known as natural substances with substantial pharmacological effects and have been used as effective painkillers. A very prominent example is morphine, which was first isolated and synthesized in the ...
Jul 17, 2024
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