Children's Hospital Colorado (Children's Colorado) successfully performed the hospital's first-ever heart and liver dual organ transplant, with support from dozens of team members across 25 different multidisciplinary care ...
Dec 19, 2025
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A newly published, post-hoc analysis of the landmark FUEL (Fontan Udenafil Exercise Longitudinal) Trial demonstrates that udenafil, a PDE5 inhibitor, significantly improves peak oxygen consumption (peak VO₂) in adolescents ...
Aug 13, 2025
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A multi-center study has identified critical risk factors that increase the likelihood of death in children with a heart defect who are awaiting or have recently undergone heart transplantation, according to findings published ...
Aug 11, 2025
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Shortly after she was born, Laura Valentine turned blue.
Jun 12, 2025
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When considering whether a child who has a single-ventricle heart defect would benefit more from biventricular repair or the Fontan procedure, heart specialists have lacked a key tool to guide them: data that shows possible ...
Apr 15, 2025
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Each child had already undergone at least three open-heart surgeries. They'd endured countless hours in doctors' offices and hospitals after being born with a serious heart condition.
Dec 31, 2024
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A long-haul flight or an overnight stay in the mountains: For many patients with a Fontan circulation (single-ventricle physiology), this was previously unimaginable, as there was insufficient medical research into how acute ...
May 8, 2024
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As patients with congenital heart diseases live longer, researchers are attempting to understand some of the other complications they may face as they age. A team from Children's Hospital of Philadelphia (CHOP) used state-of-the-art ...
Apr 24, 2024
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Patients who have had surgery to create a Fontan circulation show changes in their genetic code, which may provide a new treatment opportunity to reduce premature aging.
Apr 4, 2024
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Researchers and clinicians at Children's Hospital of Philadelphia (CHOP) have successfully tested a novel approach to help avoid performing open heart surgery on patients with severe complications related to congenital heart ...
Feb 20, 2024
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