In a first-ever human clinical trial of four adult patients, an mRNA cancer vaccine developed at the University of Florida quickly reprogrammed the immune system to attack glioblastoma, the most aggressive and lethal brain ...
May 1, 2024
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Inulin, a type of fiber found in certain plant-based foods and fiber supplements, causes inflammation in the gut and exacerbates inflammatory bowel disease in a preclinical model, according to a new study by Weill Cornell ...
May 3, 2024
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Some families call it a trial of faith. Others just call it a curse. The progressive neurological disease known as spinocerebellar ataxia 4 (SCA4) is a rare condition, but its effects on patients and their families can be ...
Apr 29, 2024
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In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published in Science Translational Medicine, a group of researchers at Massachusetts General Hospital and ...
May 1, 2024
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Researchers from the Brigham and colleagues report on the long-term follow-up of the largest study of women's health in the U.S., shedding light on the role of menopausal hormone therapy, calcium and vitamin D supplementation, ...
May 1, 2024
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Given the known risks of consuming high amounts of sugar, today many people are looking for alternative sweeteners that produce a similar taste without prompting significant weight gain and causing other health issues. While ...
A recent study from Trinity College Dublin scientists, sheds light on the complexities of achieving optimal vitamin D status across diverse populations. Despite substantial research on the determinants of vitamin D, levels ...
May 3, 2024
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Some states require that physicians report a diagnosis of dementia, including Alzheimer's disease, to the DMV. A new study suggests these mandates may have unintended consequences.
Apr 29, 2024
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Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with. Brown fat has a special job—it helps to ...
Apr 29, 2024
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The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought. In a study on rats, a team of scientists from across the ...
May 1, 2024
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Charcot–Marie–Tooth disease- (CMT), known also as Morbus Charcot-Marie-Tooth, Charcot-Marie-Tooth neuropathy, hereditary motor and sensory neuropathy (HMSN), hereditary sensorimotor neuropathy (HSMN), or peroneal muscular atrophy, is an inherited disorder of nerves (neuropathy) that takes different forms. It is predominantly characterized by loss of muscle tissue and touch sensation, in the feet, ankles and legs as it progresses over time, but also in the hands, wrists and arms in various types of the disease. Early and late onset forms occur with 'on and off' painful spasmodic muscular contractions that can be disabling when the disease activates. High arched 'Cavus Feet' are associated with the disorder. Sensory and positioning nerves in the hands and feet are often damaged, while pain nerves are left intact. Overuse of an affected hand or limb can activate symptoms ranging from numbness, to spasm, to very painful cramping. Currently incurable, this disease is one of the most common inherited neurological disorders, and was considered a type of Muscular Dystrophy for years.
Estimates of incidence vary widely from 1 in 380,000 people affected to 1 in 2,500 people affected [1]. This larger figure might equate to approximately 23,000 people in the UK and 125,000 people in the USA.
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