A Massachusetts General Hospital (MGH) research team has found how a variant in an important epigenetic enzyme—previously associated by population-based genetic studies with Crohn's disease and other immune disorders—interferes ...
Mar 3, 2017
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Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis. It is commonly treated with one of several available biological drugs that block an ...
Dec 21, 2016
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Some patients with Crohn's disease, a chronic inflammatory disease that affects the lining of the digestive tract, require surgery to remove part or all of the large intestine; however, surgery does not cure the condition ...
Dec 8, 2016
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The renin-angiotensin system (RAS) plays an important role in regulating the body's fluid levels and blood pressure. However, a new signal path in the RAS may also have a substantial influence on immune cells, as a recent ...
Nov 30, 2016
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Researchers Robiël Naziroglu and Frans Vos have developed a method for improving the assessment of MRI images in cases of Crohn's disease. In time, this may well enable more targeted monitoring and treatment of this chronic ...
Nov 21, 2016
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Researchers at University of California San Diego School of Medicine have shown that ustekinumab, a human antibody used to treat arthritis, significantly induces response and remission in patients with moderate to severe ...
Nov 17, 2016
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Scientists at the University of British Columbia have made a discovery that could potentially lead to treatments for a debilitating complication of Crohn's disease.
Sep 2, 2016
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In a study published online this week in Science Translational Medicine, investigators from Brigham and Women's Hospital and the Santa Lucia Foundation in Rome report that resolvins and maresins, molecules produced in the ...
Aug 24, 2016
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Scientists at the Centro de Investigaciones Cardiovasculares Carlos III (CNIC) have defined the key role of an immune-system receptor in the development of psoriasis, suggesting that it could serve as a therapeutic target ...
Jul 5, 2016
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Clinical trial data published in the Proceedings of the National Academy of Sciences (PNAS) demonstrates stimulating the vagus nerve with an implantable bioelectronic device significantly improved measures of disease activity ...
Jul 4, 2016
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