Diseases, Conditions, Syndromes

Isolating the molecules that trigger emphysema

Emphysema is the major debilitating component of the lethal chronic obstructive pulmonary disease (COPD), which was the third leading cause of death worldwide in 2019, causing 3.23 million deaths.

Diseases, Conditions, Syndromes

Emphysema research narrows in on FCHSD1 protein

Chronic obstructive pulmonary disease (COPD) causes illness and death worldwide. It is characterized by destruction of the walls of tiny air sacs in the lungs—known as emphysema—and a decline in lung function. Little ...

Medical research

Researchers breathe new life into COPD research using mouse models

The airways and lungs are affected by a range of diseases, but while some have been well characterized and treated, others, such as chronic obstructive pulmonary disorder (COPD), are still somewhat of an enigma. This condition ...

Medical research

Mapping the destructive path from cigarette to emphysema

From the cherry red tip of a lighted cigarette through the respiratory tract to vital lung cells, the havoc created by tobacco smoke seems almost criminal, activating genes and portions of the immune system to create inflammation ...

Genetics

COPDGene study follows emphysema patients over 10 years

Researchers at National Jewish Health evaluating computerized tomography (CT) scans of emphysema progression in the COPDGene study showed that, during a span of 10 years, participants with pre-existing emphysema who continued ...

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Emphysema is a long-term, progressive disease of the lungs that primarily causes shortness of breath. In people with emphysema, the tissues necessary to support the physical shape and function of the lungs are destroyed. It is included in a group of diseases called chronic obstructive pulmonary disease or COPD (pulmonary refers to the lungs). Emphysema is called an obstructive lung disease because the destruction of lung tissue around smaller sacs, called alveoli, makes these air sacs unable to hold their functional shape upon exhalation. It is often caused by long-term exposure to air pollution or smoking.

The term emphysema means swelling and comes from the Greek ἐμφυσᾶν emphysan meaning inflate, itself composed of ἐν en meaning in and φυσᾶν physan meaning breath, blast.

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