Immunology

Rethinking how bone marrow works with a unified framework

One huge reason why the world of medicine hasn't yet found "the cure" for hard-to-treat malignancies like acute myeloid leukemia (AML) and many other forms of cancer is that the world of science is still striving to fully ...

Oncology & Cancer

Enhanced multi-omics tool illuminates cancer progression

A new tool developed by Weill Cornell Medicine and the University of Adelaide investigators has enhanced the ability to track multiple gene mutations while simultaneously recording gene activity in individual cancer cells. ...

Oncology & Cancer

How a single protein rewires leukemia cells to fuel their growth

Cancer cells are relentless in their quest to grow and divide, often rewiring their metabolism and modifying RNA to stay one step ahead. Now, researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified ...

Oncology & Cancer

Diagnostic tool enables rapid leukemia subtype classification

Researchers at Dana-Farber Cancer Institute have developed a diagnostic tool that could transform the way acute leukemia is identified and treated. The tool, called MARLIN (Methylation- and AI-guided Rapid Leukemia Subtype ...

Oncology & Cancer

Surprising new roles discovered for known blood cancer gene DNMT3A

A gene called DNMT3A is important for guiding blood stem cells into forming all the cell types present in blood, including red blood cells, white blood cells and platelets. When this gene accumulates mutations—which might ...

Oncology & Cancer

Common intracellular toxin could help fight leukemia

All cells naturally produce formaldehyde as a byproduct of metabolism. To survive this toxic stress, both healthy and cancerous blood-forming cells rely on a built-in defense system. Now, scientists at the Lewis Katz School ...

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