New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination. Over the course of a decade of work in several study sites ...
Aug 20, 2021
0
129
Despite tremendous advances in medicine, tumors are challenging to cure because they are made up of heterogeneous cells. In other words, like human families, the individual cells of a tumor share some common traits and characteristics, ...
Aug 13, 2021
0
403
A one-two punch envisioned by many as a way to improve treatment for some blood cancers may be more challenging to implement than previously expected, according to researchers at Stanford Medicine.
Aug 4, 2021
0
195
Scientists at St. Jude Children's Research Hospital are working with colleagues in China to develop better therapy for childhood acute lymphoblastic leukemia (ALL). Results from a large phase 3 noninferiority clinical trial ...
Jul 28, 2021
0
284
For the first time, Princess Margaret researchers have mapped out where and how leukemia begins and develops in infants with Down syndrome in preclinical models, paving the way to potentially prevent this cancer in the future.
Jul 8, 2021
0
260
A new combination of drugs that may have the potential to treat a type of leukemia has been uncovered by a detailed molecular examination of leukemia cells by RIKEN researchers1.
Jun 28, 2021
0
11
A team of researchers affiliated with multiple institutions in Germany and France has found that a subgroup of T-cell acute lymphoblastic leukemia (T-ALL) mouse models benefited from a targeted therapy. In their paper published ...
The latest method under investigation to attack leukemia is a bit like exterminating cockroaches: It's a three-step process using cutting-edge technology to bait, trap, and kill leukemia cells at their root.
May 27, 2021
0
12
A team of Northwestern Medicine scientists led by Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, has identified the molecular mechanisms of ASXL1 mutations ...
May 27, 2021
0
5
T-cell acute lymphoblastic leukemia (T-ALL) is a very aggressive type of blood cancer. It is relatively rare but still draws a lot of attention as it mostly develops in children under the age of 20. The standard treatment ...
May 4, 2021
0
34
