In 2016, University of Pittsburgh researchers Dr. Farzad Esni, Ph.D., and Jing Hu, Ph.D., did an experiment in mice where they deleted one of two copies of the gene encoding an enzyme called focal adhesion kinase (FAK). They ...
May 6, 2024
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T cells—the body's foot soldiers against invaders, ranging from everyday infections to cancers—are integral to many successful immunotherapies. However, a frustrating factor is that immunotherapies do not always work.
May 6, 2024
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An accurate, affordable, environmentally and user-friendly diagnostic tool for multiple cancers—including pancreatic, gastric, and colorectal cancers—is reported in a paper in Nature Sustainability. The tool can diagnose ...
Apr 23, 2024
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New research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before ...
Apr 16, 2024
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New research from the University of Oklahoma reveals a previously unknown chain of events sparking the development of cancer cachexia, a debilitating muscle-wasting condition that almost always occurs in people diagnosed ...
Apr 12, 2024
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A new type of investigational therapeutic in development for pancreatic cancer has shown unprecedented tumor-fighting abilities in preclinical models of the disease, suggesting it has the potential to offer novel treatment ...
Apr 8, 2024
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Like alien invaders in a sci-fi movie, pancreatic cancer cells quickly adapt to the weapons used against them and find ways to survive, even in the harshest of conditions.
Apr 4, 2024
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Prof. Gabriel Nussbaum and his team at the Institute of Biomedical and Oral Research, Hebrew University-Hadassah Faculty of Dental Medicine, have recently published research in the journal Gut that uncovers a pivotal link ...
Mar 26, 2024
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Researchers at the University of Toronto's Donnelly Centre for Cellular and Biomolecular Research have found two enzymes that work against the chemotherapy drug gemcitabine, preventing it from effectively treating pancreatic ...
Mar 18, 2024
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Spinal muscular atrophy, or SMA, is the leading genetic cause of infant death. Less than a decade ago, Cold Spring Harbor Laboratory (CSHL) Professor Adrian Krainer showed this brutal disease can be treated by tweaking a ...
Mar 6, 2024
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